Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 9ES A 801 |
| Chain | Residue |
| A | VAL492 |
| A | GLY567 |
| A | GLU571 |
| A | ALA640 |
| A | ASP641 |
| A | EDO806 |
| A | LEU494 |
| A | ALA512 |
| A | LYS514 |
| A | GLU531 |
| A | VAL559 |
| A | VAL561 |
| A | GLU562 |
| A | ALA564 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | SER584 |
| A | TYR585 |
| A | HOH944 |
| A | HOH972 |
| B | ARG734 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | ARG570 |
| A | ARG627 |
| A | THR657 |
| A | ASN659 |
| A | ARG661 |
| A | HOH906 |
| A | HOH912 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 804 |
| Chain | Residue |
| A | TRP684 |
| A | TYR701 |
| A | ARG718 |
| A | MET719 |
| A | TRP737 |
| A | HOH911 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | THR746 |
| A | PHE747 |
| A | LYS748 |
| A | HOH915 |
| A | HOH920 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 806 |
| Chain | Residue |
| A | ARG627 |
| A | ASN628 |
| A | ASP641 |
| A | 9ES801 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 807 |
| Chain | Residue |
| A | ARG577 |
| A | GLY698 |
| A | SER699 |
| A | HOH948 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 808 |
| Chain | Residue |
| A | THR726 |
| A | ASN727 |
| A | GLU728 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 809 |
| Chain | Residue |
| A | LYS542 |
| A | ARG609 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 810 |
| Chain | Residue |
| A | LYS665 |
| A | SER699 |
| A | GLY703 |
| A | HOH925 |
| A | HOH947 |
| A | HOH952 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 811 |
| Chain | Residue |
| A | PRO745 |
| A | THR746 |
| A | GLN749 |
| A | HOH907 |
| A | HOH936 |
| B | ASP554 |
| B | GLY555 |
| B | PRO556 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 812 |
| Chain | Residue |
| A | GLU708 |
| A | LYS711 |
| A | LEU712 |
| A | GLU715 |
| B | GLY703 |
| B | HOH989 |
| site_id | AD4 |
| Number of Residues | 14 |
| Details | binding site for residue 9ES B 801 |
| Chain | Residue |
| B | VAL492 |
| B | LEU494 |
| B | LYS514 |
| B | GLU531 |
| B | VAL559 |
| B | VAL561 |
| B | GLU562 |
| B | ALA564 |
| B | GLU571 |
| B | LEU630 |
| B | ALA640 |
| B | ASP641 |
| B | PHE642 |
| B | HOH936 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 802 |
| Chain | Residue |
| B | ARG570 |
| B | ARG627 |
| B | THR657 |
| B | ASN659 |
| B | ARG661 |
| B | HOH917 |
| B | HOH933 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 803 |
| Chain | Residue |
| B | VAL601 |
| B | PHE694 |
| B | ASN724 |
| B | THR726 |
| B | LEU729 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 804 |
| Chain | Residue |
| B | MET719 |
| B | TRP737 |
| B | HOH922 |
| B | TRP684 |
| B | TYR701 |
| B | ARG718 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 805 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 806 |
| Chain | Residue |
| A | ASP735 |
| A | HIS738 |
| A | HOH942 |
| A | HOH984 |
| B | LEU516 |
| B | LYS517 |
| B | SER518 |
| B | PRO556 |
| B | HOH901 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 807 |
| Chain | Residue |
| B | GLU728 |
| B | ASP753 |
| B | ARG756 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 808 |
| Chain | Residue |
| B | ASP735 |
| B | GLN743 |
| B | PRO745 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
| Chain | Residue | Details |
| A | LEU484-LYS514 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ALA625 | |
| B | ALA625 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU486 | |
| B | ARG570 | |
| B | VAL629 | |
| B | GLY643 | |
| A | LEU516 | |
| A | ALA564 | |
| A | ARG570 | |
| A | VAL629 | |
| A | GLY643 | |
| B | GLU486 | |
| B | LEU516 | |
| B | ALA564 | |
| Chain | Residue | Details |
| A | LEU465 | |
| A | TYR585 | |
| A | PRO587 | |
| B | LEU465 | |
| B | TYR585 | |
| B | PRO587 | |
| Chain | Residue | Details |
| A | LYS655 | |
| A | LYS656 | |
| B | LYS655 | |
| B | LYS656 | |
| Chain | Residue | Details |
| A | MET732 | |
| B | MET732 | |
