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5UWC

Cytokine-receptor complex

Functional Information from GO Data
ChainGOidnamespacecontents
G0004896molecular_functioncytokine receptor activity
G0016020cellular_componentmembrane
I0005125molecular_functioncytokine activity
I0005135molecular_functioninterleukin-3 receptor binding
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0006955biological_processimmune response
I0007267biological_processcell-cell signaling
I0007399biological_processnervous system development
I0008083molecular_functiongrowth factor activity
I0008284biological_processpositive regulation of cell population proliferation
I0035162biological_processembryonic hemopoiesis
I0038156biological_processinterleukin-3-mediated signaling pathway
I0097696biological_processcell surface receptor signaling pathway via STAT
Functional Information from PROSITE/UniProt
site_idPS01356
Number of Residues32
DetailsHEMATOPO_REC_S_F2 Short hematopoietin receptor family 2 signature. LsCsWavGpgapaDvqYdLylnvanrrqqye..C
ChainResidueDetails
GLEU120-CYS151

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMotif: {"description":"WSXWS motif"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues6
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"25043189","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4JZJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

239492

PDB entries from 2025-07-30

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