5U7Z
Human acid ceramidase (ASAH1, aCDase) self-activated
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:29692406, ECO:0000269|PubMed:30525581 |
| Chain | Residue | Details |
| B | CYS143 | |
| D | CYS143 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Important for catalytic activity => ECO:0000269|PubMed:29692406 |
| Chain | Residue | Details |
| B | ASP162 | |
| B | ASN320 | |
| B | ARG333 | |
| D | ASP162 | |
| D | ASN320 | |
| D | ARG333 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29692406, ECO:0007744|PDB:5U7Z |
| Chain | Residue | Details |
| B | ASN173 | |
| B | ASN342 | |
| D | ASN173 | |
| D | ASN342 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN195 | |
| B | ASN348 | |
| D | ASN195 | |
| D | ASN348 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:29692406, ECO:0007744|PDB:5U7Z |
| Chain | Residue | Details |
| B | ASN259 | |
| D | ASN259 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:29692406, ECO:0007744|PDB:5U7Z |
| Chain | Residue | Details |
| B | ASN286 | |
| D | ASN286 |
