Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0004713 | molecular_function | protein tyrosine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 7YS A 9001 |
| Chain | Residue |
| A | LEU542 |
| A | ASP627 |
| A | ARG676 |
| A | ASN677 |
| A | MET679 |
| A | ALA689 |
| A | VAL550 |
| A | ALA565 |
| A | MET598 |
| A | LEU620 |
| A | PRO621 |
| A | PHE622 |
| A | MET623 |
| A | GLY626 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 7YS B 9001 |
| Chain | Residue |
| B | VAL550 |
| B | ALA565 |
| B | LYS567 |
| B | MET598 |
| B | PRO621 |
| B | PHE622 |
| B | MET623 |
| B | GLY626 |
| B | ASP627 |
| B | ARG676 |
| B | ASN677 |
| B | MET679 |
| B | ALA689 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue 7YS C 9001 |
| Chain | Residue |
| C | LEU542 |
| C | GLY543 |
| C | VAL550 |
| C | ALA565 |
| C | MET598 |
| C | PRO621 |
| C | PHE622 |
| C | MET623 |
| C | GLY626 |
| C | ASP627 |
| C | ARG676 |
| C | ASN677 |
| C | MET679 |
| C | ALA689 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue 7YS D 9001 |
| Chain | Residue |
| D | VAL550 |
| D | ALA565 |
| D | LYS567 |
| D | MET598 |
| D | PRO621 |
| D | PHE622 |
| D | MET623 |
| D | GLY626 |
| D | ASP627 |
| D | ARG676 |
| D | ASN677 |
| D | MET679 |
| D | ALA689 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGEFGAVMeGqlnqddsilk........VAVK |
| Chain | Residue | Details |
| A | LEU542-LYS567 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDLAARNCML |
| Chain | Residue | Details |
| A | PHE668-LEU680 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"18346204","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9178760","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"evidenceCode":"ECO:0000250"}]} |
