5U2H

Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001614	molecular_function	purinergic nucleotide receptor activity
A	0004931	molecular_function	extracellularly ATP-gated monoatomic cation channel activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0033198	biological_process	response to ATP
A	0098655	biological_process	monoatomic cation transmembrane transport
B	0001614	molecular_function	purinergic nucleotide receptor activity
B	0004931	molecular_function	extracellularly ATP-gated monoatomic cation channel activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0033198	biological_process	response to ATP
B	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01212
Number of Residues	27
Details	P2X_RECEPTOR ATP P2X receptors signature. GGiMGIeIyWdCNLDgwfhhCrPkYsF

Chain	Residue	Details
A	GLY249-PHE275

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