5U1F
Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0019031 | cellular_component | viral envelope |
| B | 0005198 | molecular_function | structural molecule activity |
| C | 0019031 | cellular_component | viral envelope |
| D | 0019031 | cellular_component | viral envelope |
| E | 0005198 | molecular_function | structural molecule activity |
| F | 0005198 | molecular_function | structural molecule activity |
| M | 0006955 | biological_process | immune response |
| M | 0007155 | biological_process | cell adhesion |
| M | 0015026 | molecular_function | coreceptor activity |
| M | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR199-HIS205 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI20 |
| Number of Residues | 99 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 77 |
| Details | Domain: {"description":"Ig-like C2-type 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 113 |
| Details | Domain: {"description":"Ig-like C2-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 56 |
| Details | Domain: {"description":"Ig-like C2-type 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI24 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000053","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI25 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000054","evidences":[{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
