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5U1F

Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145

Functional Information from GO Data
ChainGOidnamespacecontents
A0019031cellular_componentviral envelope
B0005198molecular_functionstructural molecule activity
C0019031cellular_componentviral envelope
D0019031cellular_componentviral envelope
E0005198molecular_functionstructural molecule activity
F0005198molecular_functionstructural molecule activity
M0006955biological_processimmune response
M0007155biological_processcell adhesion
M0015026molecular_functioncoreceptor activity
M0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
ChainResidueDetails
LTYR192-HIS198
HTYR199-HIS205

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:2001369, ECO:0000269|PubMed:2592374
ChainResidueDetails
MASN1271

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:2001369, ECO:0000269|PubMed:2592374
ChainResidueDetails
MASN1300

238268

PDB entries from 2025-07-02

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