5TT6
T4 RNA Ligase 1 (K99M)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003972 | molecular_function | RNA ligase (ATP) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016874 | molecular_function | ligase activity |
| A | 0042245 | biological_process | RNA repair |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098004 | biological_process | virus tail fiber assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | ASP272 |
| A | ATP403 |
| A | HOH522 |
| A | HOH531 |
| A | HOH536 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | HOH535 |
| A | HOH561 |
| A | ATP403 |
| A | HOH507 |
| A | HOH508 |
| A | HOH509 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residue ATP A 403 |
| Chain | Residue |
| A | TYR37 |
| A | ARG54 |
| A | MET73 |
| A | LYS75 |
| A | LEU97 |
| A | THR98 |
| A | MET99 |
| A | GLU100 |
| A | LEU104 |
| A | GLU159 |
| A | LEU179 |
| A | VAL230 |
| A | LYS240 |
| A | LYS242 |
| A | ASP272 |
| A | MG401 |
| A | MG402 |
| A | HOH507 |
| A | HOH508 |
| A | HOH522 |
| A | HOH525 |
| A | HOH531 |
| A | HOH535 |
| A | HOH536 |
| A | HOH561 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_04149","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3882425","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04149","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28223499","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04149","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16263720","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28223499","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for RNA ligase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_04149","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17068206","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
