5T2N
Engineered variant of I-OnuI meganuclease targeting the Anopheles AGAP007280 gene; harbors 38 point mutations relative to wild-type I-OnuI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004519 | molecular_function | endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | GLU22 |
| A | GLY177 |
| A | CA403 |
| A | HOH507 |
| A | HOH533 |
| B | DT15 |
| C | DA15 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | HOH508 |
| B | DC14 |
| B | HOH107 |
| C | DG16 |
| A | ALA21 |
| A | GLU178 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | GLU22 |
| A | GLU178 |
| A | CA401 |
| B | DC14 |
| B | DT15 |
| C | DA15 |
| C | DG16 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | LYS299 |
| A | HOH531 |
