5OC4
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD R361A-R362A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | GLU438 |
| A | GLY439 |
| A | ARG440 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | GOL503 |
| A | HOH627 |
| A | LYS354 |
| A | SER400 |
| A | SER412 |
| A | THR413 |
| A | LEU414 |
| A | TRP415 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ILE353 |
| A | VAL391 |
| A | GLN411 |
| A | SER433 |
| A | GLN434 |
| A | GOL502 |
| A | HOH601 |
| A | HOH606 |
| A | HOH617 |
| A | HOH627 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue CAC A 504 |
| Chain | Residue |
| A | TYR388 |
| A | GLU389 |
| A | THR390 |
| A | LYS419 |
| A | HOH610 |
| A | HOH618 |
| A | HOH625 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 67 |
| Details | Domain: {"description":"DRBM","evidences":[{"source":"PubMed","id":"26429968","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with tRNA","evidences":[{"source":"PubMed","id":"30605527","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38680565","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
