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5OAI

Structure of MDM2 with low molecular weight inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue B5K A 201
ChainResidue
ALYS51
AHOH304
AHOH308
AHOH312
AHOH315
AHOH330
AHOH333
ALEU54
AGLY58
AILE61
AMET62
AVAL93
AHIS96
AILE99
ATYR100

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues83
DetailsDomain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

245663

PDB entries from 2025-12-03

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