Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | binding site for residue SO4 A 801 |
Chain | Residue |
A | ARG570 |
A | ARG627 |
A | THR657 |
A | ASN659 |
A | ARG661 |
A | HOH904 |
A | HOH916 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 802 |
Chain | Residue |
A | LYS618 |
A | HOH941 |
A | GLY539 |
A | LYS540 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue GOL A 803 |
Chain | Residue |
A | GLN574 |
A | ASN659 |
A | ARG661 |
site_id | AC4 |
Number of Residues | 12 |
Details | binding site for residue 9K8 A 804 |
Chain | Residue |
A | LEU484 |
A | GLY485 |
A | GLU486 |
A | PHE489 |
A | GLY490 |
A | ALA512 |
A | LYS514 |
A | GLU562 |
A | ALA564 |
A | LEU630 |
A | ASP641 |
A | HOH906 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue SO4 B 801 |
Chain | Residue |
B | ARG570 |
B | ARG627 |
B | THR657 |
B | ASN659 |
B | ARG661 |
B | HOH904 |
B | HOH909 |
site_id | AC6 |
Number of Residues | 19 |
Details | binding site for Di-peptide 9K8 B 802 and LYS B 514 |
Chain | Residue |
B | LEU484 |
B | GLY485 |
B | GLU486 |
B | GLY487 |
B | GLY490 |
B | GLN491 |
B | VAL492 |
B | ALA512 |
B | VAL513 |
B | MET515 |
B | LEU528 |
B | GLU531 |
B | TYR558 |
B | VAL559 |
B | GLU562 |
B | ALA564 |
B | LEU630 |
B | ASP641 |
B | HOH910 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
Chain | Residue | Details |
A | LEU484-LYS514 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP623 | |
B | ASP623 | |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
A | LEU484 | |
B | ASN568 | |
B | ARG627 | |
B | ASP641 | |
A | LYS514 | |
A | GLU562 | |
A | ASN568 | |
A | ARG627 | |
A | ASP641 | |
B | LEU484 | |
B | LYS514 | |
B | GLU562 | |
Chain | Residue | Details |
A | TYR463 | |
A | TYR583 | |
A | TYR585 | |
B | TYR463 | |
B | TYR583 | |
B | TYR585 | |
Chain | Residue | Details |
A | TYR653 | |
A | TYR654 | |
B | TYR653 | |
B | TYR654 | |
Chain | Residue | Details |
A | TYR730 | |
B | TYR730 | |