5O1O
Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with proline bound.
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1001 |
| Chain | Residue |
| A | VAL657 |
| A | TYR700 |
| A | ARG726 |
| A | TYR730 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PRO A 1002 |
| Chain | Residue |
| A | ASP604 |
| A | GLY635 |
| A | THR724 |
| A | ARG726 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 1001 |
| Chain | Residue |
| B | THR920 |
| B | TYR918 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PRO B 1002 |
| Chain | Residue |
| B | LEU603 |
| B | ASP604 |
| B | GLY634 |
| B | GLY635 |
| B | THR724 |
| B | ARG726 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2016","submissionDatabase":"PDB data bank","title":"Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in NAD+ bound form).","authors":["Kopec J.","Yue W.W."]}},{"source":"PDB","id":"5L78","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9P4R4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99K67","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
