5NFU
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LHSpTA peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue LAY C 401 |
| Chain | Residue |
| A | TRP414 |
| A | ASP416 |
| A | ARG516 |
| C | HIS368 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for Ligand residues TPO C 370 through ALA C 371 bound to SER C 369 |
| Chain | Residue |
| A | HOH732 |
| C | SER369 |
| C | HOH501 |
| C | HOH502 |
| C | HOH503 |
| C | HOH504 |
| C | HOH505 |
| C | HOH506 |
| C | HOH508 |
| C | HOH509 |
| A | HIS489 |
| A | LEU490 |
| A | LEU491 |
| A | HIS538 |
| A | LYS540 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | SER375 | |
| A | SER450 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR498 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23455478 |
| Chain | Residue | Details |
| A | LYS492 |
