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5N9W

Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, apo structure

Replaces:  5APL
Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003824molecular_functioncatalytic activity
A0005524molecular_functionATP binding
A0005829cellular_componentcytosol
A0031177molecular_functionphosphopantetheine binding
A0043041biological_processamino acid activation for nonribosomal peptide biosynthetic process
A0044550biological_processsecondary metabolite biosynthetic process
B0000166molecular_functionnucleotide binding
B0003824molecular_functioncatalytic activity
B0005524molecular_functionATP binding
B0005829cellular_componentcytosol
B0031177molecular_functionphosphopantetheine binding
B0043041biological_processamino acid activation for nonribosomal peptide biosynthetic process
B0044550biological_processsecondary metabolite biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues1
Detailsbinding site for residue ACT A 601
ChainResidue
AARG279

site_idAC2
Number of Residues6
Detailsbinding site for residue ACT B 601
ChainResidue
BASP212
BGLY285
BGLY312
BVAL318
BHOH718
BHOH720

site_idAC3
Number of Residues8
Detailsbinding site for residue ACT B 602
ChainResidue
BTHR266
BARG443
BHIS445
BVAL448
BGLN472
BHOH717
BGLY262
BALA263

Functional Information from PROSITE/UniProt
site_idPS00455
Number of Residues12
DetailsAMP_BINDING Putative AMP-binding domain signature. IIYTSGTTGrPK
ChainResidueDetails
AILE164-LYS175

218500

PDB entries from 2024-04-17

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