Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006412 | biological_process | translation |
| A | 0006414 | biological_process | translational elongation |
| A | 0032045 | cellular_component | guanyl-nucleotide exchange factor complex |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003746 | molecular_function | translation elongation factor activity |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006412 | biological_process | translation |
| B | 0006414 | biological_process | translational elongation |
| B | 0032045 | cellular_component | guanyl-nucleotide exchange factor complex |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | THR26 |
| A | GDP403 |
| A | HOH507 |
| A | HOH513 |
| A | HOH528 |
| A | HOH535 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | HOH530 |
| B | GLU286 |
| A | ASP355 |
| A | HOH503 |
| A | HOH520 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue GDP A 403 |
| Chain | Residue |
| A | ASP22 |
| A | HIS23 |
| A | GLY24 |
| A | LYS25 |
| A | THR26 |
| A | THR27 |
| A | PHE47 |
| A | ASN136 |
| A | LYS137 |
| A | ASP139 |
| A | SER174 |
| A | ALA175 |
| A | LEU176 |
| A | MG401 |
| A | HOH507 |
| A | HOH513 |
| A | HOH525 |
| A | HOH528 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | ARG124 |
| A | GLY127 |
| A | PRO129 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 405 |
| Chain | Residue |
| A | MET113 |
| A | PRO114 |
| A | ARG117 |
| A | ARG263 |
| A | LYS264 |
| A | LEU265 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 406 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue EPE A 407 |
| Chain | Residue |
| A | LEU266 |
| A | ASP267 |
| A | GLU268 |
| A | GLY269 |
| A | ARG270 |
| A | GLU273 |
| A | HOH504 |
| A | HOH531 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue BME A 408 |
| Chain | Residue |
| A | ARG289 |
| B | LYS264 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue BME A 409 |
| Chain | Residue |
| A | ASP162 |
| B | ASP110 |
| B | PRO112 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 401 |
| Chain | Residue |
| B | THR26 |
| B | GDP403 |
| B | HOH502 |
| B | HOH503 |
| B | HOH506 |
| B | HOH539 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| A | HOH518 |
| A | HOH522 |
| A | HOH524 |
| A | HOH569 |
| B | HOH519 |
| B | HOH521 |
| site_id | AD3 |
| Number of Residues | 18 |
| Details | binding site for residue GDP B 403 |
| Chain | Residue |
| B | ASP22 |
| B | HIS23 |
| B | GLY24 |
| B | LYS25 |
| B | THR26 |
| B | THR27 |
| B | PHE47 |
| B | ASN136 |
| B | LYS137 |
| B | ASP139 |
| B | MET140 |
| B | SER174 |
| B | ALA175 |
| B | LEU176 |
| B | MG401 |
| B | HOH502 |
| B | HOH503 |
| B | HOH506 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 404 |
| Chain | Residue |
| B | GLY84 |
| B | HIS85 |
| B | GLN115 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EPE B 405 |
| Chain | Residue |
| B | GLU268 |
| B | ARG270 |
| B | GLU273 |
| B | HOH513 |
| B | HOH523 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 406 |
| Chain | Residue |
| B | THR72 |
| B | PRO73 |
| B | THR74 |
| B | ASP197 |
Functional Information from PROSITE/UniProt
| site_id | PS00301 |
| Number of Residues | 16 |
| Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS |
| Chain | Residue | Details |
| A | ASP51-SER66 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY19 | |
| A | ASP81 | |
| A | ASN136 | |
| B | GLY19 | |
| B | ASP81 | |
| B | ASN136 | |
| Chain | Residue | Details |
| A | SER2 | |
| B | SER2 | |
| Chain | Residue | Details |
| A | LYS57 | |
| B | LYS57 | |
| Chain | Residue | Details |
| A | LYS314 | |
| B | LYS314 | |
| Chain | Residue | Details |
| A | GLU383 | |
| B | GLU383 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 535 |
| Chain | Residue | Details |
| A | ASP22 | electrostatic stabiliser |
| A | LYS25 | electrostatic stabiliser |
| A | THR26 | metal ligand |
| A | HIS85 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 535 |
| Chain | Residue | Details |
| B | ASP22 | electrostatic stabiliser |
| B | LYS25 | electrostatic stabiliser |
| B | THR26 | metal ligand |
| B | HIS85 | electrostatic stabiliser |
