5M1N
Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Manganese
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ASN257 |
| A | ARG409 |
| A | TYR411 |
| A | HOH621 |
| A | HOH688 |
| A | HOH764 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 502 |
| Chain | Residue |
| A | HOH645 |
| A | HOH654 |
| A | HOH753 |
| A | ASP294 |
| A | ASP429 |
| A | HOH605 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| B | ASN257 |
| B | ARG409 |
| B | TYR411 |
| B | ARG421 |
| B | TYR423 |
| B | GLY424 |
| B | HOH612 |
| B | HOH684 |
| B | HOH720 |
| B | HOH767 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 502 |
| Chain | Residue |
| B | ASP294 |
| B | ASP429 |
| B | HOH666 |
| B | HOH770 |
| B | HOH796 |
| B | HOH808 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue BTB B 503 |
| Chain | Residue |
| B | GLU378 |
| B | SER382 |
| B | GLN418 |
| B | HOH609 |
| B | HOH626 |
| B | HOH647 |
| B | HOH763 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28100693 |
| Chain | Residue | Details |
| A | ASP294 | |
| A | ASP347 | |
| A | ASP429 | |
| B | ASP294 | |
| B | ASP347 | |
| B | ASP429 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Modulates nuclease activity => ECO:0000255|HAMAP-Rule:MF_04146 |
| Chain | Residue | Details |
| A | ASP300 | |
| B | ASP300 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Possible stabilization of Magnesium 1 => ECO:0000269|PubMed:28100693 |
| Chain | Residue | Details |
| A | ASP428 | |
| B | ASP428 |
