5LEF
Rab6A:Kif20A complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002080 | cellular_component | acrosomal membrane |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0003925 | molecular_function | G protein activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| A | 0006891 | biological_process | intra-Golgi vesicle-mediated transport |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0018125 | biological_process | peptidyl-cysteine methylation |
| A | 0019882 | biological_process | antigen processing and presentation |
| A | 0019904 | molecular_function | protein domain specific binding |
| A | 0030667 | cellular_component | secretory granule membrane |
| A | 0031175 | biological_process | neuron projection development |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031489 | molecular_function | myosin V binding |
| A | 0032588 | cellular_component | trans-Golgi network membrane |
| A | 0034067 | biological_process | protein localization to Golgi apparatus |
| A | 0034498 | biological_process | early endosome to Golgi transport |
| A | 0036064 | cellular_component | ciliary basal body |
| A | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070381 | cellular_component | endosome to plasma membrane transport vesicle |
| A | 0072385 | biological_process | minus-end-directed organelle transport along microtubule |
| A | 1903292 | biological_process | protein localization to Golgi membrane |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002080 | cellular_component | acrosomal membrane |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0003925 | molecular_function | G protein activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005802 | cellular_component | trans-Golgi network |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| B | 0006891 | biological_process | intra-Golgi vesicle-mediated transport |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0018125 | biological_process | peptidyl-cysteine methylation |
| B | 0019882 | biological_process | antigen processing and presentation |
| B | 0019904 | molecular_function | protein domain specific binding |
| B | 0030667 | cellular_component | secretory granule membrane |
| B | 0031175 | biological_process | neuron projection development |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0031489 | molecular_function | myosin V binding |
| B | 0032588 | cellular_component | trans-Golgi network membrane |
| B | 0034067 | biological_process | protein localization to Golgi apparatus |
| B | 0034498 | biological_process | early endosome to Golgi transport |
| B | 0036064 | cellular_component | ciliary basal body |
| B | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0070381 | cellular_component | endosome to plasma membrane transport vesicle |
| B | 0072385 | biological_process | minus-end-directed organelle transport along microtubule |
| B | 1903292 | biological_process | protein localization to Golgi membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue GTP A 201 |
| Chain | Residue |
| A | GLN22 |
| A | ASN40 |
| A | TYR42 |
| A | ALA44 |
| A | THR45 |
| A | GLY71 |
| A | ASN126 |
| A | LYS127 |
| A | ASP129 |
| A | LEU130 |
| A | SER156 |
| A | SER23 |
| A | ALA157 |
| A | LYS158 |
| A | MG202 |
| A | HOH306 |
| A | HOH308 |
| A | HOH315 |
| A | HOH328 |
| A | HOH365 |
| A | HOH389 |
| A | VAL24 |
| A | GLY25 |
| A | LYS26 |
| A | THR27 |
| A | SER28 |
| A | PHE38 |
| A | ASP39 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | THR27 |
| A | THR45 |
| A | GTP201 |
| A | HOH306 |
| A | HOH328 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | ARG32 |
| A | ASP36 |
| A | HOH345 |
| A | HOH347 |
| A | HOH399 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | GLU142 |
| A | PHE152 |
| A | ARG169 |
| A | HOH339 |
| A | HOH368 |
| A | HOH370 |
| B | PHE101 |
| B | GLN102 |
| B | GLU140 |
| site_id | AC5 |
| Number of Residues | 27 |
| Details | binding site for residue GTP B 201 |
| Chain | Residue |
| B | GLN22 |
| B | SER23 |
| B | VAL24 |
| B | GLY25 |
| B | LYS26 |
| B | THR27 |
| B | SER28 |
| B | PHE38 |
| B | ASP39 |
| B | ASN40 |
| B | TYR42 |
| B | ALA44 |
| B | THR45 |
| B | GLY71 |
| B | ASN126 |
| B | LYS127 |
| B | ASP129 |
| B | LEU130 |
| B | SER156 |
| B | ALA157 |
| B | LYS158 |
| B | MG202 |
| B | IPA205 |
| B | HOH308 |
| B | HOH314 |
| B | HOH319 |
| B | HOH354 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 202 |
| Chain | Residue |
| B | THR27 |
| B | THR45 |
| B | GTP201 |
| B | HOH314 |
| B | HOH319 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | ARG32 |
| B | PHE38 |
| B | HOH348 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| A | LYS146 |
| B | GLY160 |
| B | ASN162 |
| B | VAL163 |
| B | LYS164 |
| B | GLN165 |
| B | HOH301 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue IPA B 205 |
| Chain | Residue |
| B | SER28 |
| B | ASP39 |
| B | THR41 |
| B | TYR42 |
| B | GLN43 |
| B | GTP201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"O-AMP-tyrosine; by Legionella DrrA","evidences":[{"source":"PubMed","id":"21822290","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
