5LDD

Crystal structure of the heterodimeric GEF Mon1-Ccz1 in complex with Ypt7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006623	biological_process	protein targeting to vacuole
A	0016192	biological_process	vesicle-mediated transport
B	0016192	biological_process	vesicle-mediated transport
B	0035658	cellular_component	Mon1-Ccz1 complex
C	0000329	cellular_component	fungal-type vacuole membrane
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005770	cellular_component	late endosome
C	0032889	biological_process	regulation of vacuole fusion, non-autophagic
C	0043229	cellular_component	intracellular organelle
D	0006623	biological_process	protein targeting to vacuole
D	0016192	biological_process	vesicle-mediated transport
E	0016192	biological_process	vesicle-mediated transport
E	0035658	cellular_component	Mon1-Ccz1 complex
F	0000329	cellular_component	fungal-type vacuole membrane
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005770	cellular_component	late endosome
F	0032889	biological_process	regulation of vacuole fusion, non-autophagic
F	0043229	cellular_component	intracellular organelle

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 C 301

Chain	Residue
C	GLY18
C	VAL19
C	GLY20
C	LYS21
C	THR22
C	LYS38
C	HOH401
C	HOH410

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 C 302

Chain	Residue
C	GLY149
C	ILE151
C	PHE118

---

site_id	AC3
Number of Residues	12
Details	binding site for Di-peptide SO4 F 301 and LYS F 21

Chain	Residue
F	GLY15
F	ASP16
F	GLY18
F	VAL19
F	GLY20
F	THR22
F	SER23
F	LEU24
F	MET25
F	LYS38
F	ASP63
F	THR64

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VIIlGDSGVGKtsL

Chain	Residue	Details
C	VAL11-LEU24

---