5L0N

PKG I's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with RP-cGMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004692	molecular_function	cGMP-dependent protein kinase activity
A	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 A 401

Chain	Residue
A	TRP304
A	PHE305
A	GLY306
A	GLU307
A	6ZA406
A	HOH503
A	HOH522
A	HOH535

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site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 402

Chain	Residue
A	THR284
A	PHE295
A	HIS338
A	HOH501
A	HOH550
A	LYS247

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site_id	AC3
Number of Residues	3
Details	binding site for residue EDO A 403

Chain	Residue
A	ARG285
A	6ZA406
A	HOH571

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site_id	AC4
Number of Residues	3
Details	binding site for residue EDO A 404

Chain	Residue
A	GLY270
A	ASP271
A	ASP314

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site_id	AC5
Number of Residues	2
Details	binding site for residue CA A 405

Chain	Residue
A	ARG269
A	HOH616

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site_id	AC6
Number of Residues	14
Details	binding site for residue 6ZA A 406

Chain	Residue
A	ILE264
A	LEU296
A	ARG297
A	PHE305
A	GLY306
A	LYS308
A	ARG316
A	THR317
A	ALA318
A	VAL320
A	SO4401
A	EDO403
A	HOH522
A	HOH571

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Functional Information from PROSITE/UniProt

site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrQGArGDtFFIIskG

Chain	Residue	Details
A	ILE263-GLY279

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site_id	PS00889
Number of Residues	18
Details	CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGEkALqgedv......RTAnViA

Chain	Residue	Details
A	PHE305-ALA322

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24239458","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25271401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4KU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QXK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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