5KRB

GCNF DNA Binding Domain - Oct4 DR0 Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0043565	molecular_function	sequence-specific DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0008270	molecular_function	zinc ion binding
G	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 201

Chain	Residue
B	CYS75
B	CYS78
B	CYS92
B	CYS95

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 202

Chain	Residue
B	CYS111
B	CYS117
B	CYS127
B	CYS130

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN G 201

Chain	Residue
G	CYS78
G	CYS92
G	CYS95
G	CYS75

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN G 202

Chain	Residue
G	CYS111
G	CYS117
G	CYS127
G	CYS130

---

Functional Information from PROSITE/UniProt

site_id	PS00031
Number of Residues	27
Details	NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CliCg.Dratgl.HYgiisCegCkgFFkR

Chain	Residue	Details
B	CYS75-ARG101

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Zinc finger: {"description":"NR C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00407","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27984042","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KRB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---