5KO1
Pseudokinase Domain of MLKL bound to Compound 4.
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 6UY A 501 |
| Chain | Residue |
| A | ARG210 |
| A | GLU284 |
| A | CYS286 |
| A | SER335 |
| A | ASN336 |
| A | LEU338 |
| A | ALA348 |
| A | GLY349 |
| A | HOH631 |
| A | HOH683 |
| A | GLU211 |
| A | ASN212 |
| A | SER215 |
| A | LEU217 |
| A | ALA228 |
| A | LYS230 |
| A | GLU250 |
| A | MET283 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 |
| Chain | Residue | Details |
| A | LEU209 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | LYS230 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by RIPK3 => ECO:0000269|PubMed:22265413 |
| Chain | Residue | Details |
| A | THR357 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by RIPK3 => ECO:0000269|PubMed:22265413, ECO:0000269|PubMed:29883610 |
| Chain | Residue | Details |
| A | SER358 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by RIPK3 => ECO:0000250|UniProtKB:Q9D2Y4 |
| Chain | Residue | Details |
| A | SER360 |
