5K5L

Homo sapiens CCCTC-binding factor (CTCF) ZnF6-8 and H19 sequence DNA complex structure

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN E 501

Chain	Residue
E	CYS439
E	CYS442
E	HIS455
E	HIS460

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN E 502

Chain	Residue
E	CYS469
E	CYS472
E	HIS485
E	HIS489

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN F 501

Chain	Residue
F	CYS442
F	HIS455
F	HIS460
F	CYS439

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN F 502

Chain	Residue
F	CYS469
F	CYS472
F	HIS485
F	HIS489

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN G 501

Chain	Residue
G	CYS439
G	CYS442
G	HIS455
G	HIS460

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN G 502

Chain	Residue
G	CYS469
G	CYS472
G	HIS485
G	HIS489

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN G 503

Chain	Residue
G	CYS409
G	CYS412
G	HIS425
G	HIS430

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	22
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cyi..CharFtqsgtmkmHilqk.H

Chain	Residue	Details
E	CYS409-HIS430
E	CYS439-HIS460
E	CYS469-HIS489

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	69
Details	ZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
E	TYR407-HIS430
F	TYR407-HIS430
G	TYR407-HIS430

---

site_id	SWS_FT_FI2
Number of Residues	69
Details	ZN_FING: C2H2-type 7 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
E	PHE437-HIS460
F	PHE437-HIS460
G	PHE437-HIS460

---

site_id	SWS_FT_FI3
Number of Residues	66
Details	ZN_FING: C2H2-type 8 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
E	LYS467-HIS489
F	LYS467-HIS489
G	LYS467-HIS489

---