5JY0

Crystal structure of Porphyromonas endodontalis DPP11 in complex with substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0005576	cellular_component	extracellular region
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0008239	molecular_function	dipeptidyl-peptidase activity
A	0009986	cellular_component	cell surface
A	0016787	molecular_function	hydrolase activity
A	0043171	biological_process	peptide catabolic process
A	0070009	molecular_function	serine-type aminopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue TRS A 801

Chain	Residue
A	THR277
A	ARG336
A	THR648
A	GLY649
A	ASP678

---

site_id	AC2
Number of Residues	7
Details	binding site for residue TRS A 802

Chain	Residue
A	ASN632
A	SER633
A	ARG694
A	GLN261
A	GLY262
A	VAL263
A	LYS595

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"21896480","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Is essential for the Asp/Glu P1 specificity of DPP11; involved in the recognition of the Asp/Glu residue at the P1 position of substrate peptides","evidences":[{"source":"UniProtKB","id":"B2RID1","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"21896480","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---