5JXF
Crystal structure of Flavobacterium psychrophilum DPP11 in complex with dipeptide Arg-Asp
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0043171 | biological_process | peptide catabolic process |
| A | 0070009 | molecular_function | serine-type aminopeptidase activity |
| B | 0004177 | molecular_function | aminopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0043171 | biological_process | peptide catabolic process |
| B | 0070009 | molecular_function | serine-type aminopeptidase activity |
| C | 0004177 | molecular_function | aminopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0043171 | biological_process | peptide catabolic process |
| C | 0070009 | molecular_function | serine-type aminopeptidase activity |
| D | 0004177 | molecular_function | aminopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0008236 | molecular_function | serine-type peptidase activity |
| D | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0043171 | biological_process | peptide catabolic process |
| D | 0070009 | molecular_function | serine-type aminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue ARG A 801 |
| Chain | Residue |
| A | HIS83 |
| A | ASP207 |
| A | ASN210 |
| A | TRP211 |
| A | ALA321 |
| A | ASN325 |
| A | PHE660 |
| A | ASP661 |
| A | ASP802 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue ASP A 802 |
| Chain | Residue |
| A | TRP211 |
| A | THR640 |
| A | GLY641 |
| A | GLY642 |
| A | ASN643 |
| A | SER644 |
| A | PHE660 |
| A | ASP661 |
| A | ARG662 |
| A | ARG801 |
| A | HOH901 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue ARG B 801 |
| Chain | Residue |
| B | HIS83 |
| B | ASP207 |
| B | ASN210 |
| B | TRP211 |
| B | ALA321 |
| B | ASN325 |
| B | PHE660 |
| B | ASP661 |
| B | ASP802 |
| B | HOH1064 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue ASP B 802 |
| Chain | Residue |
| B | HIS83 |
| B | TRP211 |
| B | THR640 |
| B | GLY641 |
| B | GLY642 |
| B | SER644 |
| B | PHE660 |
| B | ARG662 |
| B | ARG801 |
| B | HOH910 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 801 |
| Chain | Residue |
| C | GLY627 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 801 |
| Chain | Residue |
| D | GLY627 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 802 |
| Chain | Residue |
| D | THR639 |
| D | ASN659 |
| D | HOH905 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue NA D 803 |
| Chain | Residue |
| D | GLU258 |
| D | GLY576 |
| D | TYR584 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Is essential for the Asp/Glu P1 specificity of DPP11; involved in the recognition of the Asp/Glu residue at the P1 position of substrate peptides","evidences":[{"source":"UniProtKB","id":"B2RID1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
