Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 1990380 | molecular_function | K48-linked deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue AYE A 401 |
| Chain | Residue |
| A | GLN131 |
| A | GLY135 |
| A | CYS137 |
| A | ASN318 |
| A | HIS319 |
| A | HOH509 |
| D | GLY75 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | LYS325 |
| A | LYS307 |
| A | GLU308 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG264 |
| A | LEU276 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | GLN149 |
| A | GLY309 |
| A | LEU311 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue DIO A 405 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 101 |
| Chain | Residue |
| A | HOH508 |
| D | ARG72 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| D | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"27292798","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"27292798","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interacts with activating enzyme"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for function"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PINK1","evidences":[{"source":"UniProtKB","id":"P62979","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P62979","evidenceCode":"ECO:0000250"}]} |
