5JJ4
Crystal Structure of a Variant Human Activation-induced Deoxycytidine Deaminase as an MBP fusion protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0034219 | biological_process | carbohydrate transmembrane transport |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0034219 | biological_process | carbohydrate transmembrane transport |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 39 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HVEllFLryisdwdldpgrcyrvtwftsws..........PCyd......CarhV |
| Chain | Residue | Details |
| C | HIS1056-VAL1094 |
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| C | PRO107-ASN124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P0ABF6 |
| Chain | Residue | Details |
| C | GLU1058 | |
| A | GLU1058 | |
| B | GLU1058 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27258794 |
| Chain | Residue | Details |
| C | HIS1056 | |
| C | CYS1087 | |
| C | CYS1090 | |
| A | HIS1056 | |
| A | CYS1087 | |
| A | CYS1090 | |
| B | HIS1056 | |
| B | CYS1087 | |
| B | CYS1090 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by PKA => ECO:0000269|PubMed:16387847 |
| Chain | Residue | Details |
| C | THR1027 | |
| A | THR1027 | |
| B | THR1027 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:16387847, ECO:0000269|PubMed:18722174 |
| Chain | Residue | Details |
| C | SER1038 | |
| A | SER1038 | |
| B | SER1038 |
