5JBG

Crystal structure of chicken LGP2 with 5'ppp 26-mer hairpin RNA with 3' GG overhang and ADP-AlF4-Mg2+ at 2.0 A resolution.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002376	biological_process	immune system process
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0045087	biological_process	innate immune response
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 701

Chain	Residue
A	CYS554
A	CYS557
A	CYS610
A	CYS613

---

site_id	AC2
Number of Residues	20
Details	binding site for residue ADP A 702

Chain	Residue
A	GLY27
A	ALA28
A	GLY29
A	LYS30
A	THR31
A	ARG32
A	GLU67
A	ASP444
A	ARG471
A	ALF703
A	MG704
A	HOH835
A	HOH860
A	HOH931
A	HOH954
A	SER1
A	GLU2
A	LEU3
A	HIS4
A	GLN7

---

site_id	AC3
Number of Residues	15
Details	binding site for residue ALF A 703

Chain	Residue
A	THR26
A	GLY27
A	LYS30
A	GLU132
A	ALA168
A	GLY442
A	ARG469
A	ARG471
A	ADP702
A	MG704
A	HOH805
A	HOH814
A	HOH832
A	HOH931
A	HOH958

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG A 704

Chain	Residue
A	ADP702
A	ALF703
A	HOH814
A	HOH835
A	HOH931

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 A 705

Chain	Residue
A	HIS4
A	GLY5
A	TYR6
A	GLN307
A	ARG332

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 706

Chain	Residue
A	PHE178
A	ARG503
A	SER539
A	ARG542
A	GLN543

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 A 707

Chain	Residue
A	THR414
A	ASN416
A	LYS644
A	HOH842

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 A 708

Chain	Residue
A	PHE273
A	CYS274
A	ARG275
A	LYS276
A	HOH829

---

site_id	AC9
Number of Residues	10
Details	binding site for residue SO4 X 101

Chain	Residue
A	LYS56
A	HIS135
A	HOH885
X	G20
X	C21
X	HOH212
X	HOH217
X	HOH228
X	HOH232
X	HOH238

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