5IZ0
RORgamma in complex with agonist BIO592 and Coactivator EBI96
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0003677 | molecular_function | DNA binding |
| G | 0004879 | molecular_function | nuclear receptor activity |
| G | 0005634 | cellular_component | nucleus |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 6F1 A 601 |
| Chain | Residue |
| A | CYS320 |
| A | ILE400 |
| A | HIS479 |
| A | HOH705 |
| A | HIS323 |
| A | LEU324 |
| A | ALA327 |
| A | MET358 |
| A | VAL361 |
| A | MET365 |
| A | PHE378 |
| A | PHE388 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 602 |
| Chain | Residue |
| A | PHE334 |
| A | VAL360 |
| A | ARG364 |
| A | THR421 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 603 |
| Chain | Residue |
| A | HIS458 |
| A | ARG459 |
| A | GLN460 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 604 |
| Chain | Residue |
| A | ARG296 |
| A | ARG367 |
| A | TYR369 |
| A | TYR382 |
| A | HOH722 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 605 |
| Chain | Residue |
| A | LEU362 |
| A | CYS366 |
| A | PHE403 |
| A | SER404 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 606 |
| Chain | Residue |
| A | HIS322 |
| B | HIS322 |
| B | PRO499 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 608 |
| Chain | Residue |
| A | LEU352 |
| A | GLY356 |
| A | LEU425 |
| A | ARG430 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 609 |
| Chain | Residue |
| A | TYR308 |
| A | GLN309 |
| A | LEU387 |
| A | PHE388 |
| A | ARG389 |
| A | ALA390 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | binding site for residue 6F1 B 601 |
| Chain | Residue |
| B | CYS320 |
| B | HIS323 |
| B | LEU324 |
| B | ALA327 |
| B | MET358 |
| B | VAL361 |
| B | VAL376 |
| B | PHE378 |
| B | PHE388 |
| B | LEU396 |
| B | ILE400 |
| B | PHE401 |
| B | HIS479 |
| B | HOH710 |
| B | HOH721 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 602 |
| Chain | Residue |
| A | LYS456 |
| B | HIS458 |
| B | GLN460 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 603 |
| Chain | Residue |
| B | HIS490 |
| B | PRO491 |
| B | ILE492 |
| B | VAL493 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 604 |
| Chain | Residue |
| B | TYR281 |
| B | PHE334 |
| B | VAL360 |
| B | ARG364 |
| B | THR421 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 605 |
| Chain | Residue |
| B | LEU352 |
| B | LEU425 |
| B | ARG430 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 606 |
| Chain | Residue |
| B | ARG296 |
| B | ASN370 |
| B | ASN373 |
| B | THR375 |
| B | TYR382 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 607 |
| Chain | Residue |
| B | ARG296 |
| B | ARG367 |
| B | TYR369 |
| B | TYR382 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue 6F1 D 601 |
| Chain | Residue |
| D | CYS320 |
| D | HIS323 |
| D | LEU324 |
| D | ALA327 |
| D | MET358 |
| D | VAL361 |
| D | VAL376 |
| D | PHE378 |
| D | PHE388 |
| D | ILE400 |
| D | HIS479 |
| D | HOH714 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 602 |
| Chain | Residue |
| D | CYS393 |
| D | SER394 |
| D | GLU395 |
| D | ARG482 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 603 |
| Chain | Residue |
| D | THR421 |
| D | TYR281 |
| D | PHE334 |
| D | ARG364 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 604 |
| Chain | Residue |
| D | LEU344 |
| D | CYS345 |
| D | ASP348 |
| D | GLU435 |
| site_id | AE2 |
| Number of Residues | 14 |
| Details | binding site for residue 6F1 G 601 |
| Chain | Residue |
| G | CYS320 |
| G | HIS323 |
| G | LEU324 |
| G | ALA327 |
| G | MET358 |
| G | VAL361 |
| G | MET365 |
| G | VAL376 |
| G | PHE378 |
| G | PHE388 |
| G | LEU396 |
| G | ILE400 |
| G | PHE401 |
| G | HIS479 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue CL G 602 |
| Chain | Residue |
| G | TYR281 |
| G | PHE334 |
| G | ARG364 |
| G | THR421 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue CL G 603 |
| Chain | Residue |
| G | LEU344 |
| G | CYS345 |
| G | ASP348 |
| G | GLU435 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue CL G 604 |
| Chain | Residue |
| D | LYS456 |
| G | HIS458 |
| G | GLN460 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue CL G 605 |
| Chain | Residue |
| D | HIS322 |
| D | GLU326 |
| G | GLU315 |
| G | GLU318 |
| G | ARG319 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue CL G 606 |
| Chain | Residue |
| G | HIS490 |
| G | PRO491 |
| G | ILE492 |
| G | VAL493 |
