5HZH
Crystal structure of photoinhibitable Rac1 containing C450A mutant LOV2 domain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue GTP A 401 |
| Chain | Residue |
| A | GLY12 |
| A | PRO34 |
| A | THR35 |
| A | THR207 |
| A | GLY209 |
| A | LYS265 |
| A | ASP267 |
| A | LEU268 |
| A | SER307 |
| A | ALA308 |
| A | LEU309 |
| A | ALA13 |
| A | MG403 |
| A | HOH502 |
| A | HOH504 |
| A | HOH509 |
| A | VAL14 |
| A | GLY15 |
| A | LYS16 |
| A | THR17 |
| A | CYS18 |
| A | PHE28 |
| A | TYR32 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue FMN A 402 |
| Chain | Residue |
| A | VAL63 |
| A | THR65 |
| A | ASN72 |
| A | ASN96 |
| A | ALA97 |
| A | ARG98 |
| A | LEU100 |
| A | GLN101 |
| A | VAL110 |
| A | ILE113 |
| A | ARG114 |
| A | ILE117 |
| A | LEU127 |
| A | ASN129 |
| A | ASN139 |
| A | PHE141 |
| A | PHE156 |
| A | GLY158 |
| A | GLN160 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | THR17 |
| A | THR35 |
| A | ASP206 |
| A | GTP401 |
| A | HOH502 |
| A | HOH504 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | ASP212 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CA A 405 |
| Chain | Residue |
| A | ASP152 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11090627, ECO:0007744|PDB:1E96, ECO:0007744|PDB:2WKP, ECO:0007744|PDB:2WKQ, ECO:0007744|PDB:2WKR |
| Chain | Residue | Details |
| A | ALA13 | |
| A | GLY30 | |
| A | GLY209 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11090627, ECO:0007744|PDB:1E96, ECO:0007744|PDB:2WKP, ECO:0007744|PDB:2WKQ, ECO:0007744|PDB:2WKR, ECO:0007744|PDB:5HZH |
| Chain | Residue | Details |
| A | LYS265 | |
| A | ALA308 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538 |
| Chain | Residue | Details |
| A | TYR32 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103 |
| Chain | Residue | Details |
| A | THR35 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:10617634 |
| Chain | Residue | Details |
| A | SER220 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704 |
| Chain | Residue | Details |
| A | TYR32 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB, and by P.sordellii toxin TcsL; alternate => ECO:0000269|PubMed:19744486, ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059 |
| Chain | Residue | Details |
| A | THR35 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:18093184 |
| Chain | Residue | Details |
| A | LYS296 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23512198 |
| Chain | Residue | Details |
| A | LYS315 |
