Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | HIS170 |
| A | LYS223 |
| A | ASP223 |
| S | GLY10 |
| S | LEU11 |
| S | GLN122 |
| S | THR124 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | ASP223 |
| A | HOH404 |
| T | GLN13 |
| A | HIS170 |
| A | LYS223 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | HIS170 |
| B | TYR171 |
| B | ASP223 |
| B | HOH424 |
| T | GOL202 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | SER125 |
| B | MET126 |
| B | ARG239 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue TWN S 201 |
| Chain | Residue |
| B | THR147 |
| S | ARG45 |
| S | TYR95 |
| S | TRP117 |
| S | TWN202 |
| T | ARG45 |
| T | TRP117 |
| T | TWN201 |
| T | HOH341 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue TWN S 202 |
| Chain | Residue |
| A | TYR149 |
| B | TYR149 |
| S | ARG45 |
| S | HIS100 |
| S | LEU103 |
| S | GLU115 |
| S | TRP117 |
| S | TWN201 |
| T | GLU44 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 S 203 |
| Chain | Residue |
| S | SER52 |
| S | SER54 |
| S | GLY56 |
| S | SER57 |
| S | HOH328 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue MES S 204 |
| Chain | Residue |
| A | MET126 |
| A | ARG239 |
| A | HOH403 |
| S | LEU11 |
| S | GLN13 |
| S | SER127 |
| S | HOH317 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue TWN T 201 |
| Chain | Residue |
| A | TYR149 |
| S | GLU44 |
| S | TWN201 |
| T | PHE37 |
| T | ARG45 |
| T | LEU103 |
| T | GLU115 |
| T | TRP117 |
| T | HOH314 |
| T | HOH340 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL T 202 |
| Chain | Residue |
| B | HIS170 |
| B | LYS223 |
| B | ASP223 |
| B | LYS224 |
| B | GOL301 |
| T | GLY10 |
| T | LEU11 |
| T | GLN122 |
| T | THR124 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL T 203 |
| Chain | Residue |
| T | SER7 |
| T | GLY8 |
| T | GLY9 |
| T | THR121 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
| Chain | Residue | Details |
| A | SER146 | |
| B | SER146 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | GLN145 | |
| B | GLN145 | |
