5GAN

The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom

Functional Information from GO Data

Chain	GOid	namespace	contents
2	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
2	0000398	biological_process	mRNA splicing, via spliceosome
2	0000932	cellular_component	P-body
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005681	cellular_component	spliceosomal complex
2	0005688	cellular_component	U6 snRNP
2	0005730	cellular_component	nucleolus
2	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
2	0005737	cellular_component	cytoplasm
2	0006364	biological_process	rRNA processing
2	0006397	biological_process	mRNA processing
2	0008033	biological_process	tRNA processing
2	0008380	biological_process	RNA splicing
2	0032991	cellular_component	protein-containing complex
2	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2	0071001	cellular_component	U4/U6 snRNP
2	0071011	cellular_component	precatalytic spliceosome
2	0071013	cellular_component	catalytic step 2 spliceosome
2	1990726	cellular_component	Lsm1-7-Pat1 complex
3	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
3	0000398	biological_process	mRNA splicing, via spliceosome
3	0000932	cellular_component	P-body
3	0003723	molecular_function	RNA binding
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005681	cellular_component	spliceosomal complex
3	0005688	cellular_component	U6 snRNP
3	0005730	cellular_component	nucleolus
3	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
3	0005737	cellular_component	cytoplasm
3	0006364	biological_process	rRNA processing
3	0006397	biological_process	mRNA processing
3	0008033	biological_process	tRNA processing
3	0008380	biological_process	RNA splicing
3	0032991	cellular_component	protein-containing complex
3	0033962	biological_process	P-body assembly
3	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
3	0071001	cellular_component	U4/U6 snRNP
3	0071011	cellular_component	precatalytic spliceosome
3	0071013	cellular_component	catalytic step 2 spliceosome
3	1990726	cellular_component	Lsm1-7-Pat1 complex
4	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
4	0000387	biological_process	spliceosomal snRNP assembly
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0000932	cellular_component	P-body
4	0000956	biological_process	nuclear-transcribed mRNA catabolic process
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005681	cellular_component	spliceosomal complex
4	0005688	cellular_component	U6 snRNP
4	0005730	cellular_component	nucleolus
4	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
4	0005737	cellular_component	cytoplasm
4	0006364	biological_process	rRNA processing
4	0006396	biological_process	RNA processing
4	0006397	biological_process	mRNA processing
4	0008033	biological_process	tRNA processing
4	0008380	biological_process	RNA splicing
4	0017070	molecular_function	U6 snRNA binding
4	0033962	biological_process	P-body assembly
4	0042149	biological_process	cellular response to glucose starvation
4	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4	0071001	cellular_component	U4/U6 snRNP
4	0097525	cellular_component	spliceosomal snRNP complex
4	0097526	cellular_component	spliceosomal tri-snRNP complex
4	1990726	cellular_component	Lsm1-7-Pat1 complex
5	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
5	0000398	biological_process	mRNA splicing, via spliceosome
5	0000932	cellular_component	P-body
5	0000956	biological_process	nuclear-transcribed mRNA catabolic process
5	0003723	molecular_function	RNA binding
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005681	cellular_component	spliceosomal complex
5	0005688	cellular_component	U6 snRNP
5	0005730	cellular_component	nucleolus
5	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
5	0006364	biological_process	rRNA processing
5	0006397	biological_process	mRNA processing
5	0008033	biological_process	tRNA processing
5	0008380	biological_process	RNA splicing
5	0032991	cellular_component	protein-containing complex
5	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5	0071001	cellular_component	U4/U6 snRNP
5	1990726	cellular_component	Lsm1-7-Pat1 complex
6	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
6	0000398	biological_process	mRNA splicing, via spliceosome
6	0000932	cellular_component	P-body
6	0003723	molecular_function	RNA binding
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005681	cellular_component	spliceosomal complex
6	0005688	cellular_component	U6 snRNP
6	0005730	cellular_component	nucleolus
6	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
6	0005737	cellular_component	cytoplasm
6	0006364	biological_process	rRNA processing
6	0006397	biological_process	mRNA processing
6	0008033	biological_process	tRNA processing
6	0008380	biological_process	RNA splicing
6	0030490	biological_process	maturation of SSU-rRNA
6	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
6	0071001	cellular_component	U4/U6 snRNP
6	0120114	cellular_component	Sm-like protein family complex
6	1990726	cellular_component	Lsm1-7-Pat1 complex
7	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0000932	cellular_component	P-body
7	0000956	biological_process	nuclear-transcribed mRNA catabolic process
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005681	cellular_component	spliceosomal complex
7	0005688	cellular_component	U6 snRNP
7	0005730	cellular_component	nucleolus
7	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
7	0005737	cellular_component	cytoplasm
7	0006364	biological_process	rRNA processing
7	0006397	biological_process	mRNA processing
7	0008033	biological_process	tRNA processing
7	0008380	biological_process	RNA splicing
7	0030490	biological_process	maturation of SSU-rRNA
7	0032991	cellular_component	protein-containing complex
7	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
7	0071001	cellular_component	U4/U6 snRNP
7	0071004	cellular_component	U2-type prespliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	0097526	cellular_component	spliceosomal tri-snRNP complex
7	1990726	cellular_component	Lsm1-7-Pat1 complex
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003723	molecular_function	RNA binding
8	0003729	molecular_function	mRNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005681	cellular_component	spliceosomal complex
8	0005688	cellular_component	U6 snRNP
8	0005730	cellular_component	nucleolus
8	0005737	cellular_component	cytoplasm
8	0006364	biological_process	rRNA processing
8	0006397	biological_process	mRNA processing
8	0008033	biological_process	tRNA processing
8	0008380	biological_process	RNA splicing
8	0032991	cellular_component	protein-containing complex
8	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
8	0071001	cellular_component	U4/U6 snRNP
8	0071011	cellular_component	precatalytic spliceosome
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
A	0000386	molecular_function	second spliceosomal transesterification activity
A	0000387	biological_process	spliceosomal snRNP assembly
A	0000389	biological_process	mRNA 3'-splice site recognition
A	0000395	biological_process	mRNA 5'-splice site recognition
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0005737	cellular_component	cytoplasm
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0017070	molecular_function	U6 snRNA binding
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0097157	molecular_function	pre-mRNA intronic binding
b	0000243	cellular_component	commitment complex
b	0000245	biological_process	spliceosomal complex assembly
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000395	biological_process	mRNA 5'-splice site recognition
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003674	molecular_function	molecular_function
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005737	cellular_component	cytoplasm
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0032991	cellular_component	protein-containing complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0043229	cellular_component	intracellular organelle
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070990	molecular_function	snRNP binding
b	0071001	cellular_component	U4/U6 snRNP
b	0071004	cellular_component	U2-type prespliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990904	cellular_component	ribonucleoprotein complex
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003676	molecular_function	nucleic acid binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0000244	biological_process	spliceosomal tri-snRNP complex assembly
C	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
C	0000387	biological_process	spliceosomal snRNP assembly
C	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005681	cellular_component	spliceosomal complex
C	0005682	cellular_component	U5 snRNP
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0030623	molecular_function	U5 snRNA binding
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0000243	cellular_component	commitment complex
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000395	biological_process	mRNA 5'-splice site recognition
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0003729	molecular_function	mRNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006396	biological_process	RNA processing
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0071001	cellular_component	U4/U6 snRNP
d	0071004	cellular_component	U2-type prespliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0097525	cellular_component	spliceosomal snRNP complex
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0000243	cellular_component	commitment complex
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000395	biological_process	mRNA 5'-splice site recognition
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005737	cellular_component	cytoplasm
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0032991	cellular_component	protein-containing complex
e	0034715	cellular_component	pICln-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0043229	cellular_component	intracellular organelle
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071001	cellular_component	U4/U6 snRNP
e	0071004	cellular_component	U2-type prespliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990935	molecular_function	splicing factor binding
f	0000243	cellular_component	commitment complex
f	0000245	biological_process	spliceosomal complex assembly
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000395	biological_process	mRNA 5'-splice site recognition
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005737	cellular_component	cytoplasm
f	0006397	biological_process	mRNA processing
f	0008266	molecular_function	poly(U) RNA binding
f	0008380	biological_process	RNA splicing
f	0034715	cellular_component	pICln-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071001	cellular_component	U4/U6 snRNP
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
f	1990935	molecular_function	splicing factor binding
F	0000244	biological_process	spliceosomal tri-snRNP complex assembly
F	0000387	biological_process	spliceosomal snRNP assembly
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003674	molecular_function	molecular_function
F	0003723	molecular_function	RNA binding
F	0005634	cellular_component	nucleus
F	0005681	cellular_component	spliceosomal complex
F	0005687	cellular_component	U4 snRNP
F	0005739	cellular_component	mitochondrion
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
F	0071001	cellular_component	U4/U6 snRNP
F	0071011	cellular_component	precatalytic spliceosome
F	0097526	cellular_component	spliceosomal tri-snRNP complex
g	0000243	cellular_component	commitment complex
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000395	biological_process	mRNA 5'-splice site recognition
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003674	molecular_function	molecular_function
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005737	cellular_component	cytoplasm
g	0006397	biological_process	mRNA processing
g	0008150	biological_process	biological_process
g	0008380	biological_process	RNA splicing
g	0032991	cellular_component	protein-containing complex
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071001	cellular_component	U4/U6 snRNP
g	0071004	cellular_component	U2-type prespliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
G	0000245	biological_process	spliceosomal complex assembly
G	0000387	biological_process	spliceosomal snRNP assembly
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0003674	molecular_function	molecular_function
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005681	cellular_component	spliceosomal complex
G	0005687	cellular_component	U4 snRNP
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0071001	cellular_component	U4/U6 snRNP
h	0000243	cellular_component	commitment complex
h	0000245	biological_process	spliceosomal complex assembly
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000395	biological_process	mRNA 5'-splice site recognition
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0003729	molecular_function	mRNA binding
h	0005634	cellular_component	nucleus
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006396	biological_process	RNA processing
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0071001	cellular_component	U4/U6 snRNP
h	0071004	cellular_component	U2-type prespliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0097525	cellular_component	spliceosomal snRNP complex
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990904	cellular_component	ribonucleoprotein complex
H	0000245	biological_process	spliceosomal complex assembly
H	0000393	biological_process	spliceosomal conformational changes to generate catalytic conformation
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003674	molecular_function	molecular_function
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005681	cellular_component	spliceosomal complex
H	0005687	cellular_component	U4 snRNP
H	0006397	biological_process	mRNA processing
H	0008380	biological_process	RNA splicing
H	0017070	molecular_function	U6 snRNA binding
H	0030621	molecular_function	U4 snRNA binding
H	0034247	biological_process	snoRNA splicing
H	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
H	0071001	cellular_component	U4/U6 snRNP
j	0000243	cellular_component	commitment complex
j	0000245	biological_process	spliceosomal complex assembly
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000395	biological_process	mRNA 5'-splice site recognition
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003674	molecular_function	molecular_function
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006397	biological_process	mRNA processing
j	0008150	biological_process	biological_process
j	0008380	biological_process	RNA splicing
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0032991	cellular_component	protein-containing complex
j	0034715	cellular_component	pICln-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0071001	cellular_component	U4/U6 snRNP
j	0071004	cellular_component	U2-type prespliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	1903241	biological_process	U2-type prespliceosome assembly
j	1990904	cellular_component	ribonucleoprotein complex
J	0000244	biological_process	spliceosomal tri-snRNP complex assembly
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0003674	molecular_function	molecular_function
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005681	cellular_component	spliceosomal complex
J	0005682	cellular_component	U5 snRNP
J	0006396	biological_process	RNA processing
J	0006397	biological_process	mRNA processing
J	0008150	biological_process	biological_process
J	0008380	biological_process	RNA splicing
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0071001	cellular_component	U4/U6 snRNP
J	0071013	cellular_component	catalytic step 2 spliceosome
k	0000243	cellular_component	commitment complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000395	biological_process	mRNA 5'-splice site recognition
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003674	molecular_function	molecular_function
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005737	cellular_component	cytoplasm
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0032991	cellular_component	protein-containing complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043229	cellular_component	intracellular organelle
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070990	molecular_function	snRNP binding
k	0071001	cellular_component	U4/U6 snRNP
k	0071004	cellular_component	U2-type prespliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990904	cellular_component	ribonucleoprotein complex
K	0000245	biological_process	spliceosomal complex assembly
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
K	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005681	cellular_component	spliceosomal complex
K	0005687	cellular_component	U4 snRNP
K	0005730	cellular_component	nucleolus
K	0006364	biological_process	rRNA processing
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0030490	biological_process	maturation of SSU-rRNA
K	0030621	molecular_function	U4 snRNA binding
K	0031428	cellular_component	box C/D methylation guide snoRNP complex
K	0032040	cellular_component	small-subunit processome
K	0034511	molecular_function	U3 snoRNA binding
K	0042254	biological_process	ribosome biogenesis
K	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
K	0071001	cellular_component	U4/U6 snRNP
K	0071011	cellular_component	precatalytic spliceosome
K	1990904	cellular_component	ribonucleoprotein complex
l	0000243	cellular_component	commitment complex
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000395	biological_process	mRNA 5'-splice site recognition
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0003729	molecular_function	mRNA binding
l	0005634	cellular_component	nucleus
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006396	biological_process	RNA processing
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071001	cellular_component	U4/U6 snRNP
l	0071004	cellular_component	U2-type prespliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	0097525	cellular_component	spliceosomal snRNP complex
l	0097526	cellular_component	spliceosomal tri-snRNP complex
l	1903241	biological_process	U2-type prespliceosome assembly
l	1990904	cellular_component	ribonucleoprotein complex
m	0000243	cellular_component	commitment complex
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000395	biological_process	mRNA 5'-splice site recognition
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003674	molecular_function	molecular_function
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008150	biological_process	biological_process
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0032991	cellular_component	protein-containing complex
m	0034715	cellular_component	pICln-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071001	cellular_component	U4/U6 snRNP
m	0071004	cellular_component	U2-type prespliceosome
m	0071011	cellular_component	precatalytic spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	1903241	biological_process	U2-type prespliceosome assembly
m	1990904	cellular_component	ribonucleoprotein complex
n	0000243	cellular_component	commitment complex
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000395	biological_process	mRNA 5'-splice site recognition
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0003729	molecular_function	mRNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006396	biological_process	RNA processing
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0034715	cellular_component	pICln-Sm protein complex
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071001	cellular_component	U4/U6 snRNP
n	0071004	cellular_component	U2-type prespliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097525	cellular_component	spliceosomal snRNP complex
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990904	cellular_component	ribonucleoprotein complex
p	0000243	cellular_component	commitment complex
p	0000245	biological_process	spliceosomal complex assembly
p	0000387	biological_process	spliceosomal snRNP assembly
p	0000395	biological_process	mRNA 5'-splice site recognition
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005681	cellular_component	spliceosomal complex
p	0005682	cellular_component	U5 snRNP
p	0005685	cellular_component	U1 snRNP
p	0005686	cellular_component	U2 snRNP
p	0005687	cellular_component	U4 snRNP
p	0005737	cellular_component	cytoplasm
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0032991	cellular_component	protein-containing complex
p	0034715	cellular_component	pICln-Sm protein complex
p	0036261	biological_process	7-methylguanosine cap hypermethylation
p	0043229	cellular_component	intracellular organelle
p	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
p	0071001	cellular_component	U4/U6 snRNP
p	0071004	cellular_component	U2-type prespliceosome
p	0071011	cellular_component	precatalytic spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
p	1990935	molecular_function	splicing factor binding
q	0000243	cellular_component	commitment complex
q	0000245	biological_process	spliceosomal complex assembly
q	0000387	biological_process	spliceosomal snRNP assembly
q	0000395	biological_process	mRNA 5'-splice site recognition
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0003723	molecular_function	RNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005681	cellular_component	spliceosomal complex
q	0005682	cellular_component	U5 snRNP
q	0005685	cellular_component	U1 snRNP
q	0005686	cellular_component	U2 snRNP
q	0005687	cellular_component	U4 snRNP
q	0005737	cellular_component	cytoplasm
q	0006397	biological_process	mRNA processing
q	0008266	molecular_function	poly(U) RNA binding
q	0008380	biological_process	RNA splicing
q	0034715	cellular_component	pICln-Sm protein complex
q	0036261	biological_process	7-methylguanosine cap hypermethylation
q	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
q	0071001	cellular_component	U4/U6 snRNP
q	0071013	cellular_component	catalytic step 2 spliceosome
q	0120114	cellular_component	Sm-like protein family complex
q	1903241	biological_process	U2-type prespliceosome assembly
q	1990935	molecular_function	splicing factor binding
r	0000243	cellular_component	commitment complex
r	0000245	biological_process	spliceosomal complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000395	biological_process	mRNA 5'-splice site recognition
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003674	molecular_function	molecular_function
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005681	cellular_component	spliceosomal complex
r	0005682	cellular_component	U5 snRNP
r	0005685	cellular_component	U1 snRNP
r	0005686	cellular_component	U2 snRNP
r	0005687	cellular_component	U4 snRNP
r	0005737	cellular_component	cytoplasm
r	0006397	biological_process	mRNA processing
r	0008150	biological_process	biological_process
r	0008380	biological_process	RNA splicing
r	0032991	cellular_component	protein-containing complex
r	0034719	cellular_component	SMN-Sm protein complex
r	0036261	biological_process	7-methylguanosine cap hypermethylation
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0071001	cellular_component	U4/U6 snRNP
r	0071004	cellular_component	U2-type prespliceosome
r	0071011	cellular_component	precatalytic spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0097526	cellular_component	spliceosomal tri-snRNP complex
r	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. GINIDSLKFNELVKLM

Chain	Residue	Details
B	GLY174-MET189

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IGSAshDmTWRLWDA

Chain	Residue	Details
H	ILE280-ALA294
H	VAL322-ILE336
H	VAL364-ILE378

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVpSRvaLG

Chain	Residue	Details
K	CYS71-GLY88

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
C	GLY140
C	ASP214
C	ASN268

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
C	SER85

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
C	THR88

---