Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU A 900 |
| Chain | Residue |
| A | TYR450 |
| A | TYR732 |
| A | PRO478 |
| A | LEU479 |
| A | THR480 |
| A | ARG485 |
| A | GLY653 |
| A | SER654 |
| A | THR655 |
| A | GLU705 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GLU B 900 |
| Chain | Residue |
| B | TYR450 |
| B | PRO478 |
| B | THR480 |
| B | ARG485 |
| B | LEU650 |
| B | GLY653 |
| B | SER654 |
| B | THR655 |
| B | GLU705 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GLU C 900 |
| Chain | Residue |
| C | TYR450 |
| C | PRO478 |
| C | THR480 |
| C | ARG485 |
| C | GLY653 |
| C | SER654 |
| C | THR655 |
| C | GLU705 |
| C | MET708 |
| C | TYR732 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 901 |
| Chain | Residue |
| A | HIS412 |
| B | ASP454 |
| B | ASP456 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 902 |
| Chain | Residue |
| A | GLU431 |
| A | HIS435 |
| C | GLU678 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 901 |
| Chain | Residue |
| B | HIS412 |
| C | LYS409 |
| C | GLU419 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 902 |
| Chain | Residue |
| B | GLU431 |
| B | HIS435 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN C 902 |
| Chain | Residue |
| C | GLU431 |
| C | HIS435 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO478 | |
| B | SER654 | |
| B | THR655 | |
| B | GLU705 | |
| C | PRO478 | |
| C | THR480 | |
| C | ARG485 | |
| C | SER654 | |
| C | THR655 | |
| C | GLU705 | |
| A | THR480 | |
| A | ARG485 | |
| A | SER654 | |
| A | THR655 | |
| A | GLU705 | |
| B | PRO478 | |
| B | THR480 | |
| B | ARG485 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG453 | |
| A | ARG660 | |
| A | LYS752 | |
| B | ARG453 | |
| B | ARG660 | |
| B | LYS752 | |
| C | ARG453 | |
| C | ARG660 | |
| C | LYS752 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE633 | |
| B | ILE633 | |
| C | ILE633 | |
| Chain | Residue | Details |
| A | SER662 | |
| B | SER662 | |
| C | SER662 | |
| Chain | Residue | Details |
| A | SER696 | |
| B | SER696 | |
| C | SER696 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN385 | |
| A | ASN392 | |
| B | ASN385 | |
| B | ASN392 | |
| C | ASN385 | |
| C | ASN392 | |
