5FCB

Murine SMPDL3A in complex with AMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003689	molecular_function	DNA clamp loader activity
A	0004767	molecular_function	sphingomyelin phosphodiesterase activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006338	biological_process	chromatin remodeling
A	0006685	biological_process	sphingomyelin catabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0008270	molecular_function	zinc ion binding
A	0009143	biological_process	nucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0046872	molecular_function	metal ion binding
A	0061775	molecular_function	cohesin loader activity
A	0140584	molecular_function	chromatin extrusion motor activity
A	0140588	biological_process	chromatin looping
A	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
A	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
A	0160049	biological_process	negative regulation of cGAS/STING signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:26792860

Chain	Residue	Details
A	ASP42
A	HIS44
A	ASP107
A	ASN148
A	HIS249
A	HIS290
A	HIS292

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:26792860

Chain	Residue	Details
A	HIS111
A	HIS149
A	TYR257

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site_id	SWS_FT_FI3
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255, ECO:0000269|PubMed:26792860

Chain	Residue	Details
A	ASN66
A	ASN128
A	ASN235
A	ASN353
A	ASN364

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN219

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