5FB0
Crystal Structure of a PHD finger bound to histone H3 T3ph peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 901 |
| Chain | Residue |
| A | CYS705 |
| A | CYS708 |
| A | HIS725 |
| A | CYS728 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 902 |
| Chain | Residue |
| A | CYS717 |
| A | THR719 |
| A | CYS720 |
| A | CYS742 |
| A | CYS745 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 901 |
| Chain | Residue |
| C | CYS705 |
| C | CYS708 |
| C | HIS725 |
| C | CYS728 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 902 |
| Chain | Residue |
| C | CYS717 |
| C | THR719 |
| C | CYS720 |
| C | CYS742 |
| C | CYS745 |
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 41 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. CevCnkwgrl.......................................FcCdt..Cprs.FHehChipsveanknp..................................WsCifC |
| Chain | Residue | Details |
| A | CYS705-CYS745 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| D | ARG2 | |
| F | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| D | TPO3 | |
| F | TPO3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | LYS4 | |
| F | LYS4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| D | GLN5 | |
| F | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| D | THR6 | |
| F | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| D | ARG8 | |
| F | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | LYS9 | |
| F | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588 |
| Chain | Residue | Details |
| D | SER10 | |
| F | SER10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC and CHEK1 => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:18243098, ECO:0000269|PubMed:22901803 |
| Chain | Residue | Details |
| D | THR11 | |
| F | THR11 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| D | LYS14 | |
| F | LYS14 |
