5EM2

Crystal structure of the Erb1-Ytm1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042254	biological_process	ribosome biogenesis
B	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0006364	biological_process	rRNA processing
B	0030687	cellular_component	preribosome, large subunit precursor
B	0042254	biological_process	ribosome biogenesis
B	0042273	biological_process	ribosomal large subunit biogenesis
B	0043021	molecular_function	ribonucleoprotein complex binding
B	0070545	cellular_component	PeBoW complex
C	0042254	biological_process	ribosome biogenesis
D	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0006364	biological_process	rRNA processing
D	0030687	cellular_component	preribosome, large subunit precursor
D	0042254	biological_process	ribosome biogenesis
D	0042273	biological_process	ribosomal large subunit biogenesis
D	0043021	molecular_function	ribonucleoprotein complex binding
D	0070545	cellular_component	PeBoW complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 901

Chain	Residue
A	GLN487
A	VAL488
A	TRP489
A	SER490

---

site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 902

Chain	Residue
A	VAL466
A	LEU482
A	LEU483
B	GLN318

---

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 903

Chain	Residue
A	ASN500
A	ARG721
A	ALA722
A	LEU777
A	ASP778
A	ARG457

---

site_id	AC4
Number of Residues	3
Details	binding site for residue EDO A 904

Chain	Residue
A	ARG450
A	ASP794
A	ARG798

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO A 905

Chain	Residue
A	THR712
A	ARG714
A	PHE715
A	HOH1010

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO A 906

Chain	Residue
A	HIS642
A	LEU647
A	LYS668
A	GLY686
A	ASP687
A	LEU703
C	ASP704

---

site_id	AC7
Number of Residues	2
Details	binding site for residue MG A 907

Chain	Residue
A	ASP687
C	ASP687

---

site_id	AC8
Number of Residues	2
Details	binding site for residue EDO C 901

Chain	Residue
C	ARG714
C	EDO902

---

site_id	AC9
Number of Residues	2
Details	binding site for residue EDO C 902

Chain	Residue
C	THR712
C	EDO901

---

site_id	AD1
Number of Residues	2
Details	binding site for residue EDO D 501

Chain	Residue
D	LYS181
D	ASP229

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO D 502

Chain	Residue
D	ALA245
D	ASP246
D	HIS296
D	THR297
D	ALA298

---

site_id	AD3
Number of Residues	7
Details	binding site for residue EDO D 503

Chain	Residue
D	ASP410
D	GLY411
D	THR412
D	GLU442
D	ARG443
D	TRP446
D	PRO455

---

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATGgdDgTVRVWEL

Chain	Residue	Details
A	LEU468-LEU482
B	VAL146-ALA160
B	LEU404-LEU418

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	78
Details	Repeat: {"description":"WD 1","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Repeat: {"description":"WD 2","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	84
Details	Repeat: {"description":"WD 3","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	76
Details	Repeat: {"description":"WD 4","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	78
Details	Repeat: {"description":"WD 5","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	80
Details	Repeat: {"description":"WD 6","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	60
Details	Repeat: {"description":"WD 7","evidences":[{"source":"HAMAP-Rule","id":"MF_03027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	76
Details	Repeat: {"description":"WD 2","evidences":[{"source":"HAMAP-Rule","id":"MF_03029","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	78
Details	Repeat: {"description":"WD 3","evidences":[{"source":"HAMAP-Rule","id":"MF_03029","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	82
Details	Repeat: {"description":"WD 5","evidences":[{"source":"HAMAP-Rule","id":"MF_03029","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	80
Details	Repeat: {"description":"WD 6","evidences":[{"source":"HAMAP-Rule","id":"MF_03029","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---