5EM2
Crystal structure of the Erb1-Ytm1 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042254 | biological_process | ribosome biogenesis |
| B | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| B | 0000466 | biological_process | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005730 | cellular_component | nucleolus |
| B | 0006364 | biological_process | rRNA processing |
| B | 0030687 | cellular_component | preribosome, large subunit precursor |
| B | 0042254 | biological_process | ribosome biogenesis |
| B | 0042273 | biological_process | ribosomal large subunit biogenesis |
| B | 0043021 | molecular_function | ribonucleoprotein complex binding |
| C | 0042254 | biological_process | ribosome biogenesis |
| D | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| D | 0000466 | biological_process | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005730 | cellular_component | nucleolus |
| D | 0006364 | biological_process | rRNA processing |
| D | 0030687 | cellular_component | preribosome, large subunit precursor |
| D | 0042254 | biological_process | ribosome biogenesis |
| D | 0042273 | biological_process | ribosomal large subunit biogenesis |
| D | 0043021 | molecular_function | ribonucleoprotein complex binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 901 |
| Chain | Residue |
| A | GLN487 |
| A | VAL488 |
| A | TRP489 |
| A | SER490 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 902 |
| Chain | Residue |
| A | VAL466 |
| A | LEU482 |
| A | LEU483 |
| B | GLN318 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 903 |
| Chain | Residue |
| A | ASN500 |
| A | ARG721 |
| A | ALA722 |
| A | LEU777 |
| A | ASP778 |
| A | ARG457 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 904 |
| Chain | Residue |
| A | ARG450 |
| A | ASP794 |
| A | ARG798 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 905 |
| Chain | Residue |
| A | THR712 |
| A | ARG714 |
| A | PHE715 |
| A | HOH1010 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 906 |
| Chain | Residue |
| A | HIS642 |
| A | LEU647 |
| A | LYS668 |
| A | GLY686 |
| A | ASP687 |
| A | LEU703 |
| C | ASP704 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 907 |
| Chain | Residue |
| A | ASP687 |
| C | ASP687 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 901 |
| Chain | Residue |
| C | ARG714 |
| C | EDO902 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 902 |
| Chain | Residue |
| C | THR712 |
| C | EDO901 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 501 |
| Chain | Residue |
| D | LYS181 |
| D | ASP229 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| D | ALA245 |
| D | ASP246 |
| D | HIS296 |
| D | THR297 |
| D | ALA298 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| D | ASP410 |
| D | GLY411 |
| D | THR412 |
| D | GLU442 |
| D | ARG443 |
| D | TRP446 |
| D | PRO455 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. VLSAsyDgLLRIWNA |
| Chain | Residue | Details |
| B | VAL146-ALA160 | |
| B | LEU404-LEU418 | |
| A | LEU468-LEU482 |
