5EJI
Crystal structure of NAD kinase W78F mutant from Listeria monocytogenes in complex with NADP/Mn++/PPi
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003951 | molecular_function | NAD+ kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006741 | biological_process | NADP+ biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019674 | biological_process | NAD+ metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | GLY44 |
| A | GLU123 |
| A | ASP150 |
| A | SER158 |
| A | THR161 |
| A | ALA162 |
| A | TYR163 |
| A | SER166 |
| A | ALA185 |
| A | ILE187 |
| A | MN302 |
| A | ASP45 |
| A | POP303 |
| A | GLY46 |
| A | LEU49 |
| A | LEU72 |
| A | GLY73 |
| A | PHE74 |
| A | TYR75 |
| A | ASN122 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue MN A 302 |
| Chain | Residue |
| A | NAP301 |
| A | POP303 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue POP A 303 |
| Chain | Residue |
| A | GLY44 |
| A | ASP45 |
| A | GLY46 |
| A | THR47 |
| A | NAP301 |
| A | MN302 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue CIT A 304 |
| Chain | Residue |
| A | TYR100 |
| A | HIS173 |
| A | HIS204 |
| A | HIS205 |
| A | ARG247 |
| A | PHE251 |
| A | PRO252 |
| A | PHE253 |
| A | ARG256 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00361","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17686780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00361","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17686780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00361","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17686780","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
