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5DKP

Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004176molecular_functionATP-dependent peptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005737cellular_componentcytoplasm
A0006508biological_processproteolysis
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0008236molecular_functionserine-type peptidase activity
A0009368cellular_componentendopeptidase Clp complex
A0051117molecular_functionATPase binding
B0004176molecular_functionATP-dependent peptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005737cellular_componentcytoplasm
B0006508biological_processproteolysis
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0008236molecular_functionserine-type peptidase activity
B0009368cellular_componentendopeptidase Clp complex
B0051117molecular_functionATPase binding
C0004176molecular_functionATP-dependent peptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005737cellular_componentcytoplasm
C0006508biological_processproteolysis
C0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
C0008236molecular_functionserine-type peptidase activity
C0009368cellular_componentendopeptidase Clp complex
C0051117molecular_functionATPase binding
D0004176molecular_functionATP-dependent peptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005737cellular_componentcytoplasm
D0006508biological_processproteolysis
D0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
D0008236molecular_functionserine-type peptidase activity
D0009368cellular_componentendopeptidase Clp complex
D0051117molecular_functionATPase binding
E0004176molecular_functionATP-dependent peptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005737cellular_componentcytoplasm
E0006508biological_processproteolysis
E0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
E0008236molecular_functionserine-type peptidase activity
E0009368cellular_componentendopeptidase Clp complex
E0051117molecular_functionATPase binding
F0004176molecular_functionATP-dependent peptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005737cellular_componentcytoplasm
F0006508biological_processproteolysis
F0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
F0008236molecular_functionserine-type peptidase activity
F0009368cellular_componentendopeptidase Clp complex
F0051117molecular_functionATPase binding
G0004176molecular_functionATP-dependent peptidase activity
G0004252molecular_functionserine-type endopeptidase activity
G0005737cellular_componentcytoplasm
G0006508biological_processproteolysis
G0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
G0008236molecular_functionserine-type peptidase activity
G0009368cellular_componentendopeptidase Clp complex
G0051117molecular_functionATPase binding
H0004176molecular_functionATP-dependent peptidase activity
H0004252molecular_functionserine-type endopeptidase activity
H0005737cellular_componentcytoplasm
H0006508biological_processproteolysis
H0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
H0008236molecular_functionserine-type peptidase activity
H0009368cellular_componentendopeptidase Clp complex
H0051117molecular_functionATPase binding
I0004176molecular_functionATP-dependent peptidase activity
I0004252molecular_functionserine-type endopeptidase activity
I0005737cellular_componentcytoplasm
I0006508biological_processproteolysis
I0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
I0008236molecular_functionserine-type peptidase activity
I0009368cellular_componentendopeptidase Clp complex
I0051117molecular_functionATPase binding
J0004176molecular_functionATP-dependent peptidase activity
J0004252molecular_functionserine-type endopeptidase activity
J0005737cellular_componentcytoplasm
J0006508biological_processproteolysis
J0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
J0008236molecular_functionserine-type peptidase activity
J0009368cellular_componentendopeptidase Clp complex
J0051117molecular_functionATPase binding
K0004176molecular_functionATP-dependent peptidase activity
K0004252molecular_functionserine-type endopeptidase activity
K0005737cellular_componentcytoplasm
K0006508biological_processproteolysis
K0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
K0008236molecular_functionserine-type peptidase activity
K0009368cellular_componentendopeptidase Clp complex
K0051117molecular_functionATPase binding
L0004176molecular_functionATP-dependent peptidase activity
L0004252molecular_functionserine-type endopeptidase activity
L0005737cellular_componentcytoplasm
L0006508biological_processproteolysis
L0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
L0008236molecular_functionserine-type peptidase activity
L0009368cellular_componentendopeptidase Clp complex
L0051117molecular_functionATPase binding
M0004176molecular_functionATP-dependent peptidase activity
M0004252molecular_functionserine-type endopeptidase activity
M0005737cellular_componentcytoplasm
M0006508biological_processproteolysis
M0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
M0008236molecular_functionserine-type peptidase activity
M0009368cellular_componentendopeptidase Clp complex
M0051117molecular_functionATPase binding
N0004176molecular_functionATP-dependent peptidase activity
N0004252molecular_functionserine-type endopeptidase activity
N0005737cellular_componentcytoplasm
N0006508biological_processproteolysis
N0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
N0008236molecular_functionserine-type peptidase activity
N0009368cellular_componentendopeptidase Clp complex
N0051117molecular_functionATPase binding
a0004176molecular_functionATP-dependent peptidase activity
a0004252molecular_functionserine-type endopeptidase activity
a0005737cellular_componentcytoplasm
a0006508biological_processproteolysis
a0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
a0008236molecular_functionserine-type peptidase activity
a0009368cellular_componentendopeptidase Clp complex
a0051117molecular_functionATPase binding
b0004176molecular_functionATP-dependent peptidase activity
b0004252molecular_functionserine-type endopeptidase activity
b0005737cellular_componentcytoplasm
b0006508biological_processproteolysis
b0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
b0008236molecular_functionserine-type peptidase activity
b0009368cellular_componentendopeptidase Clp complex
b0051117molecular_functionATPase binding
c0004176molecular_functionATP-dependent peptidase activity
c0004252molecular_functionserine-type endopeptidase activity
c0005737cellular_componentcytoplasm
c0006508biological_processproteolysis
c0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
c0008236molecular_functionserine-type peptidase activity
c0009368cellular_componentendopeptidase Clp complex
c0051117molecular_functionATPase binding
d0004176molecular_functionATP-dependent peptidase activity
d0004252molecular_functionserine-type endopeptidase activity
d0005737cellular_componentcytoplasm
d0006508biological_processproteolysis
d0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
d0008236molecular_functionserine-type peptidase activity
d0009368cellular_componentendopeptidase Clp complex
d0051117molecular_functionATPase binding
e0004176molecular_functionATP-dependent peptidase activity
e0004252molecular_functionserine-type endopeptidase activity
e0005737cellular_componentcytoplasm
e0006508biological_processproteolysis
e0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
e0008236molecular_functionserine-type peptidase activity
e0009368cellular_componentendopeptidase Clp complex
e0051117molecular_functionATPase binding
f0004176molecular_functionATP-dependent peptidase activity
f0004252molecular_functionserine-type endopeptidase activity
f0005737cellular_componentcytoplasm
f0006508biological_processproteolysis
f0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
f0008236molecular_functionserine-type peptidase activity
f0009368cellular_componentendopeptidase Clp complex
f0051117molecular_functionATPase binding
g0004176molecular_functionATP-dependent peptidase activity
g0004252molecular_functionserine-type endopeptidase activity
g0005737cellular_componentcytoplasm
g0006508biological_processproteolysis
g0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
g0008236molecular_functionserine-type peptidase activity
g0009368cellular_componentendopeptidase Clp complex
g0051117molecular_functionATPase binding
h0004176molecular_functionATP-dependent peptidase activity
h0004252molecular_functionserine-type endopeptidase activity
h0005737cellular_componentcytoplasm
h0006508biological_processproteolysis
h0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
h0008236molecular_functionserine-type peptidase activity
h0009368cellular_componentendopeptidase Clp complex
h0051117molecular_functionATPase binding
i0004176molecular_functionATP-dependent peptidase activity
i0004252molecular_functionserine-type endopeptidase activity
i0005737cellular_componentcytoplasm
i0006508biological_processproteolysis
i0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
i0008236molecular_functionserine-type peptidase activity
i0009368cellular_componentendopeptidase Clp complex
i0051117molecular_functionATPase binding
j0004176molecular_functionATP-dependent peptidase activity
j0004252molecular_functionserine-type endopeptidase activity
j0005737cellular_componentcytoplasm
j0006508biological_processproteolysis
j0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
j0008236molecular_functionserine-type peptidase activity
j0009368cellular_componentendopeptidase Clp complex
j0051117molecular_functionATPase binding
k0004176molecular_functionATP-dependent peptidase activity
k0004252molecular_functionserine-type endopeptidase activity
k0005737cellular_componentcytoplasm
k0006508biological_processproteolysis
k0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
k0008236molecular_functionserine-type peptidase activity
k0009368cellular_componentendopeptidase Clp complex
k0051117molecular_functionATPase binding
l0004176molecular_functionATP-dependent peptidase activity
l0004252molecular_functionserine-type endopeptidase activity
l0005737cellular_componentcytoplasm
l0006508biological_processproteolysis
l0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
l0008236molecular_functionserine-type peptidase activity
l0009368cellular_componentendopeptidase Clp complex
l0051117molecular_functionATPase binding
m0004176molecular_functionATP-dependent peptidase activity
m0004252molecular_functionserine-type endopeptidase activity
m0005737cellular_componentcytoplasm
m0006508biological_processproteolysis
m0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
m0008236molecular_functionserine-type peptidase activity
m0009368cellular_componentendopeptidase Clp complex
m0051117molecular_functionATPase binding
n0004176molecular_functionATP-dependent peptidase activity
n0004252molecular_functionserine-type endopeptidase activity
n0005737cellular_componentcytoplasm
n0006508biological_processproteolysis
n0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
n0008236molecular_functionserine-type peptidase activity
n0009368cellular_componentendopeptidase Clp complex
n0051117molecular_functionATPase binding
Functional Information from PROSITE/UniProt
site_idPS00381
Number of Residues12
DetailsCLP_PROTEASE_SER Endopeptidase Clp serine active site. TlcLGqAASMGA
ChainResidueDetails
ATHR94-ALA105

site_idPS00382
Number of Residues14
DetailsCLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnsrIMIHQP
ChainResidueDetails
AARG116-PRO129

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
ASER102
BSER102
CSER102
DSER102
ESER102
FSER102
GSER102
HSER102
ISER102
JSER102
KSER102
LSER102
MSER102
NSER102
aSER102
bSER102
cSER102
dSER102
eSER102
fSER102
gSER102
hSER102
iSER102
jSER102
kSER102
lSER102
mSER102
nSER102

site_idSWS_FT_FI2
Number of Residues28
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
AHIS127
BHIS127
CHIS127
DHIS127
EHIS127
FHIS127
GHIS127
HHIS127
IHIS127
JHIS127
KHIS127
LHIS127
MHIS127
NHIS127
aHIS127
bHIS127
cHIS127
dHIS127
eHIS127
fHIS127
gHIS127
hHIS127
iHIS127
jHIS127
kHIS127
lHIS127
mHIS127
nHIS127

219140

PDB entries from 2024-05-01

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