Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5D80

Crystal Structure of Yeast V1-ATPase in the Autoinhibited Form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
A	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
A	0046034	biological_process	ATP metabolic process
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005524	molecular_function	ATP binding
B	0016887	molecular_function	ATP hydrolysis activity
B	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
B	0046034	biological_process	ATP metabolic process
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005524	molecular_function	ATP binding
C	0016887	molecular_function	ATP hydrolysis activity
C	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
C	0046034	biological_process	ATP metabolic process
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0000139	cellular_component	Golgi membrane
D	0000166	molecular_function	nucleotide binding
D	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
D	0000329	cellular_component	fungal-type vacuole membrane
D	0000425	biological_process	pexophagy
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005773	cellular_component	vacuole
D	0005774	cellular_component	vacuolar membrane
D	0006811	biological_process	monoatomic ion transport
D	0006874	biological_process	intracellular calcium ion homeostasis
D	0007035	biological_process	vacuolar acidification
D	0010494	cellular_component	cytoplasmic stress granule
D	0016020	cellular_component	membrane
D	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
D	0033176	cellular_component	proton-transporting V-type ATPase complex
D	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
D	0046034	biological_process	ATP metabolic process
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	0048388	biological_process	endosomal lumen acidification
D	0055085	biological_process	transmembrane transport
D	0061795	biological_process	Golgi lumen acidification
D	1902600	biological_process	proton transmembrane transport
D	1902906	biological_process	proteasome storage granule assembly
D	1990816	cellular_component	vacuole-mitochondrion membrane contact site
E	0000139	cellular_component	Golgi membrane
E	0000166	molecular_function	nucleotide binding
E	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
E	0000329	cellular_component	fungal-type vacuole membrane
E	0000425	biological_process	pexophagy
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005773	cellular_component	vacuole
E	0005774	cellular_component	vacuolar membrane
E	0006811	biological_process	monoatomic ion transport
E	0006874	biological_process	intracellular calcium ion homeostasis
E	0007035	biological_process	vacuolar acidification
E	0010494	cellular_component	cytoplasmic stress granule
E	0016020	cellular_component	membrane
E	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
E	0033176	cellular_component	proton-transporting V-type ATPase complex
E	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
E	0046034	biological_process	ATP metabolic process
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	0048388	biological_process	endosomal lumen acidification
E	0055085	biological_process	transmembrane transport
E	0061795	biological_process	Golgi lumen acidification
E	1902600	biological_process	proton transmembrane transport
E	1902906	biological_process	proteasome storage granule assembly
E	1990816	cellular_component	vacuole-mitochondrion membrane contact site
F	0000139	cellular_component	Golgi membrane
F	0000166	molecular_function	nucleotide binding
F	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
F	0000329	cellular_component	fungal-type vacuole membrane
F	0000425	biological_process	pexophagy
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005773	cellular_component	vacuole
F	0005774	cellular_component	vacuolar membrane
F	0006811	biological_process	monoatomic ion transport
F	0006874	biological_process	intracellular calcium ion homeostasis
F	0007035	biological_process	vacuolar acidification
F	0010494	cellular_component	cytoplasmic stress granule
F	0016020	cellular_component	membrane
F	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
F	0033176	cellular_component	proton-transporting V-type ATPase complex
F	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
F	0046034	biological_process	ATP metabolic process
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	0048388	biological_process	endosomal lumen acidification
F	0055085	biological_process	transmembrane transport
F	0061795	biological_process	Golgi lumen acidification
F	1902600	biological_process	proton transmembrane transport
F	1902906	biological_process	proteasome storage granule assembly
F	1990816	cellular_component	vacuole-mitochondrion membrane contact site
G	0000139	cellular_component	Golgi membrane
G	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
G	0000329	cellular_component	fungal-type vacuole membrane
G	0005515	molecular_function	protein binding
G	0005773	cellular_component	vacuole
G	0005774	cellular_component	vacuolar membrane
G	0006811	biological_process	monoatomic ion transport
G	0007035	biological_process	vacuolar acidification
G	0016020	cellular_component	membrane
G	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0048388	biological_process	endosomal lumen acidification
G	0061795	biological_process	Golgi lumen acidification
G	1902600	biological_process	proton transmembrane transport
H	0000139	cellular_component	Golgi membrane
H	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
H	0000329	cellular_component	fungal-type vacuole membrane
H	0005515	molecular_function	protein binding
H	0005773	cellular_component	vacuole
H	0005774	cellular_component	vacuolar membrane
H	0006811	biological_process	monoatomic ion transport
H	0007035	biological_process	vacuolar acidification
H	0016020	cellular_component	membrane
H	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
H	0033176	cellular_component	proton-transporting V-type ATPase complex
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	0048388	biological_process	endosomal lumen acidification
H	0061795	biological_process	Golgi lumen acidification
H	1902600	biological_process	proton transmembrane transport
I	0000139	cellular_component	Golgi membrane
I	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
I	0000329	cellular_component	fungal-type vacuole membrane
I	0005515	molecular_function	protein binding
I	0005773	cellular_component	vacuole
I	0005774	cellular_component	vacuolar membrane
I	0006811	biological_process	monoatomic ion transport
I	0007035	biological_process	vacuolar acidification
I	0016020	cellular_component	membrane
I	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
I	0033176	cellular_component	proton-transporting V-type ATPase complex
I	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0048388	biological_process	endosomal lumen acidification
I	0061795	biological_process	Golgi lumen acidification
I	1902600	biological_process	proton transmembrane transport
J	0000139	cellular_component	Golgi membrane
J	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
J	0000329	cellular_component	fungal-type vacuole membrane
J	0005515	molecular_function	protein binding
J	0005773	cellular_component	vacuole
J	0005774	cellular_component	vacuolar membrane
J	0006811	biological_process	monoatomic ion transport
J	0007035	biological_process	vacuolar acidification
J	0016020	cellular_component	membrane
J	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
J	0016887	molecular_function	ATP hydrolysis activity
J	0033176	cellular_component	proton-transporting V-type ATPase complex
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	0048388	biological_process	endosomal lumen acidification
J	0061795	biological_process	Golgi lumen acidification
J	1902600	biological_process	proton transmembrane transport
K	0000139	cellular_component	Golgi membrane
K	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
K	0000329	cellular_component	fungal-type vacuole membrane
K	0005515	molecular_function	protein binding
K	0005773	cellular_component	vacuole
K	0005774	cellular_component	vacuolar membrane
K	0006811	biological_process	monoatomic ion transport
K	0007035	biological_process	vacuolar acidification
K	0016020	cellular_component	membrane
K	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
K	0033176	cellular_component	proton-transporting V-type ATPase complex
K	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	0048388	biological_process	endosomal lumen acidification
K	0061795	biological_process	Golgi lumen acidification
K	1902600	biological_process	proton transmembrane transport
L	0000139	cellular_component	Golgi membrane
L	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
L	0000329	cellular_component	fungal-type vacuole membrane
L	0005515	molecular_function	protein binding
L	0005773	cellular_component	vacuole
L	0005774	cellular_component	vacuolar membrane
L	0006811	biological_process	monoatomic ion transport
L	0007035	biological_process	vacuolar acidification
L	0016020	cellular_component	membrane
L	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
L	0016887	molecular_function	ATP hydrolysis activity
L	0033176	cellular_component	proton-transporting V-type ATPase complex
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	0048388	biological_process	endosomal lumen acidification
L	0061795	biological_process	Golgi lumen acidification
L	1902600	biological_process	proton transmembrane transport
M	0000139	cellular_component	Golgi membrane
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0000329	cellular_component	fungal-type vacuole membrane
M	0005515	molecular_function	protein binding
M	0005773	cellular_component	vacuole
M	0005774	cellular_component	vacuolar membrane
M	0006811	biological_process	monoatomic ion transport
M	0007035	biological_process	vacuolar acidification
M	0016020	cellular_component	membrane
M	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
M	0033176	cellular_component	proton-transporting V-type ATPase complex
M	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0048388	biological_process	endosomal lumen acidification
M	0061795	biological_process	Golgi lumen acidification
M	1902600	biological_process	proton transmembrane transport
N	0000139	cellular_component	Golgi membrane
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0000329	cellular_component	fungal-type vacuole membrane
N	0005515	molecular_function	protein binding
N	0005773	cellular_component	vacuole
N	0005774	cellular_component	vacuolar membrane
N	0006811	biological_process	monoatomic ion transport
N	0007035	biological_process	vacuolar acidification
N	0016020	cellular_component	membrane
N	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
N	0016887	molecular_function	ATP hydrolysis activity
N	0033176	cellular_component	proton-transporting V-type ATPase complex
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0048388	biological_process	endosomal lumen acidification
N	0061795	biological_process	Golgi lumen acidification
N	1902600	biological_process	proton transmembrane transport
O	0000139	cellular_component	Golgi membrane
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0000329	cellular_component	fungal-type vacuole membrane
O	0005515	molecular_function	protein binding
O	0005773	cellular_component	vacuole
O	0005774	cellular_component	vacuolar membrane
O	0006811	biological_process	monoatomic ion transport
O	0007035	biological_process	vacuolar acidification
O	0016020	cellular_component	membrane
O	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
O	0033176	cellular_component	proton-transporting V-type ATPase complex
O	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
O	0034220	biological_process	monoatomic ion transmembrane transport
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0048388	biological_process	endosomal lumen acidification
O	0061795	biological_process	Golgi lumen acidification
O	1902600	biological_process	proton transmembrane transport
a	0005524	molecular_function	ATP binding
a	0016887	molecular_function	ATP hydrolysis activity
a	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
a	0046034	biological_process	ATP metabolic process
a	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
a	1902600	biological_process	proton transmembrane transport
b	0005524	molecular_function	ATP binding
b	0016887	molecular_function	ATP hydrolysis activity
b	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
b	0046034	biological_process	ATP metabolic process
b	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
b	1902600	biological_process	proton transmembrane transport
c	0005524	molecular_function	ATP binding
c	0016887	molecular_function	ATP hydrolysis activity
c	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
c	0046034	biological_process	ATP metabolic process
c	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
c	1902600	biological_process	proton transmembrane transport
d	0000139	cellular_component	Golgi membrane
d	0000166	molecular_function	nucleotide binding
d	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
d	0000329	cellular_component	fungal-type vacuole membrane
d	0000425	biological_process	pexophagy
d	0005515	molecular_function	protein binding
d	0005524	molecular_function	ATP binding
d	0005737	cellular_component	cytoplasm
d	0005773	cellular_component	vacuole
d	0005774	cellular_component	vacuolar membrane
d	0006811	biological_process	monoatomic ion transport
d	0006874	biological_process	intracellular calcium ion homeostasis
d	0007035	biological_process	vacuolar acidification
d	0010494	cellular_component	cytoplasmic stress granule
d	0016020	cellular_component	membrane
d	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
d	0033176	cellular_component	proton-transporting V-type ATPase complex
d	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
d	0046034	biological_process	ATP metabolic process
d	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
d	0048388	biological_process	endosomal lumen acidification
d	0055085	biological_process	transmembrane transport
d	0061795	biological_process	Golgi lumen acidification
d	1902600	biological_process	proton transmembrane transport
d	1902906	biological_process	proteasome storage granule assembly
d	1990816	cellular_component	vacuole-mitochondrion membrane contact site
e	0000139	cellular_component	Golgi membrane
e	0000166	molecular_function	nucleotide binding
e	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
e	0000329	cellular_component	fungal-type vacuole membrane
e	0000425	biological_process	pexophagy
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005773	cellular_component	vacuole
e	0005774	cellular_component	vacuolar membrane
e	0006811	biological_process	monoatomic ion transport
e	0006874	biological_process	intracellular calcium ion homeostasis
e	0007035	biological_process	vacuolar acidification
e	0010494	cellular_component	cytoplasmic stress granule
e	0016020	cellular_component	membrane
e	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
e	0033176	cellular_component	proton-transporting V-type ATPase complex
e	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
e	0046034	biological_process	ATP metabolic process
e	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
e	0048388	biological_process	endosomal lumen acidification
e	0055085	biological_process	transmembrane transport
e	0061795	biological_process	Golgi lumen acidification
e	1902600	biological_process	proton transmembrane transport
e	1902906	biological_process	proteasome storage granule assembly
e	1990816	cellular_component	vacuole-mitochondrion membrane contact site
f	0000139	cellular_component	Golgi membrane
f	0000166	molecular_function	nucleotide binding
f	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
f	0000329	cellular_component	fungal-type vacuole membrane
f	0000425	biological_process	pexophagy
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005737	cellular_component	cytoplasm
f	0005773	cellular_component	vacuole
f	0005774	cellular_component	vacuolar membrane
f	0006811	biological_process	monoatomic ion transport
f	0006874	biological_process	intracellular calcium ion homeostasis
f	0007035	biological_process	vacuolar acidification
f	0010494	cellular_component	cytoplasmic stress granule
f	0016020	cellular_component	membrane
f	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
f	0033176	cellular_component	proton-transporting V-type ATPase complex
f	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
f	0046034	biological_process	ATP metabolic process
f	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
f	0048388	biological_process	endosomal lumen acidification
f	0055085	biological_process	transmembrane transport
f	0061795	biological_process	Golgi lumen acidification
f	1902600	biological_process	proton transmembrane transport
f	1902906	biological_process	proteasome storage granule assembly
f	1990816	cellular_component	vacuole-mitochondrion membrane contact site
g	0000139	cellular_component	Golgi membrane
g	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
g	0000329	cellular_component	fungal-type vacuole membrane
g	0005515	molecular_function	protein binding
g	0005773	cellular_component	vacuole
g	0005774	cellular_component	vacuolar membrane
g	0006811	biological_process	monoatomic ion transport
g	0007035	biological_process	vacuolar acidification
g	0016020	cellular_component	membrane
g	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
g	0033176	cellular_component	proton-transporting V-type ATPase complex
g	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
g	0048388	biological_process	endosomal lumen acidification
g	0061795	biological_process	Golgi lumen acidification
g	1902600	biological_process	proton transmembrane transport
h	0000139	cellular_component	Golgi membrane
h	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
h	0000329	cellular_component	fungal-type vacuole membrane
h	0005515	molecular_function	protein binding
h	0005773	cellular_component	vacuole
h	0005774	cellular_component	vacuolar membrane
h	0006811	biological_process	monoatomic ion transport
h	0007035	biological_process	vacuolar acidification
h	0016020	cellular_component	membrane
h	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
h	0033176	cellular_component	proton-transporting V-type ATPase complex
h	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
h	0048388	biological_process	endosomal lumen acidification
h	0061795	biological_process	Golgi lumen acidification
h	1902600	biological_process	proton transmembrane transport
i	0000139	cellular_component	Golgi membrane
i	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
i	0000329	cellular_component	fungal-type vacuole membrane
i	0005515	molecular_function	protein binding
i	0005773	cellular_component	vacuole
i	0005774	cellular_component	vacuolar membrane
i	0006811	biological_process	monoatomic ion transport
i	0007035	biological_process	vacuolar acidification
i	0016020	cellular_component	membrane
i	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
i	0033176	cellular_component	proton-transporting V-type ATPase complex
i	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
i	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
i	0048388	biological_process	endosomal lumen acidification
i	0061795	biological_process	Golgi lumen acidification
i	1902600	biological_process	proton transmembrane transport
j	0000139	cellular_component	Golgi membrane
j	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
j	0000329	cellular_component	fungal-type vacuole membrane
j	0005515	molecular_function	protein binding
j	0005773	cellular_component	vacuole
j	0005774	cellular_component	vacuolar membrane
j	0006811	biological_process	monoatomic ion transport
j	0007035	biological_process	vacuolar acidification
j	0016020	cellular_component	membrane
j	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
j	0016887	molecular_function	ATP hydrolysis activity
j	0033176	cellular_component	proton-transporting V-type ATPase complex
j	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
j	0048388	biological_process	endosomal lumen acidification
j	0061795	biological_process	Golgi lumen acidification
j	1902600	biological_process	proton transmembrane transport
k	0000139	cellular_component	Golgi membrane
k	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
k	0000329	cellular_component	fungal-type vacuole membrane
k	0005515	molecular_function	protein binding
k	0005773	cellular_component	vacuole
k	0005774	cellular_component	vacuolar membrane
k	0006811	biological_process	monoatomic ion transport
k	0007035	biological_process	vacuolar acidification
k	0016020	cellular_component	membrane
k	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
k	0033176	cellular_component	proton-transporting V-type ATPase complex
k	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
k	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
k	0048388	biological_process	endosomal lumen acidification
k	0061795	biological_process	Golgi lumen acidification
k	1902600	biological_process	proton transmembrane transport
l	0000139	cellular_component	Golgi membrane
l	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
l	0000329	cellular_component	fungal-type vacuole membrane
l	0005515	molecular_function	protein binding
l	0005773	cellular_component	vacuole
l	0005774	cellular_component	vacuolar membrane
l	0006811	biological_process	monoatomic ion transport
l	0007035	biological_process	vacuolar acidification
l	0016020	cellular_component	membrane
l	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
l	0016887	molecular_function	ATP hydrolysis activity
l	0033176	cellular_component	proton-transporting V-type ATPase complex
l	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
l	0048388	biological_process	endosomal lumen acidification
l	0061795	biological_process	Golgi lumen acidification
l	1902600	biological_process	proton transmembrane transport
m	0000139	cellular_component	Golgi membrane
m	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
m	0000329	cellular_component	fungal-type vacuole membrane
m	0005515	molecular_function	protein binding
m	0005773	cellular_component	vacuole
m	0005774	cellular_component	vacuolar membrane
m	0006811	biological_process	monoatomic ion transport
m	0007035	biological_process	vacuolar acidification
m	0016020	cellular_component	membrane
m	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
m	0033176	cellular_component	proton-transporting V-type ATPase complex
m	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
m	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
m	0048388	biological_process	endosomal lumen acidification
m	0061795	biological_process	Golgi lumen acidification
m	1902600	biological_process	proton transmembrane transport
n	0000139	cellular_component	Golgi membrane
n	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
n	0000329	cellular_component	fungal-type vacuole membrane
n	0005515	molecular_function	protein binding
n	0005773	cellular_component	vacuole
n	0005774	cellular_component	vacuolar membrane
n	0006811	biological_process	monoatomic ion transport
n	0007035	biological_process	vacuolar acidification
n	0016020	cellular_component	membrane
n	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
n	0016887	molecular_function	ATP hydrolysis activity
n	0033176	cellular_component	proton-transporting V-type ATPase complex
n	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
n	0048388	biological_process	endosomal lumen acidification
n	0061795	biological_process	Golgi lumen acidification
n	1902600	biological_process	proton transmembrane transport
o	0000139	cellular_component	Golgi membrane
o	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
o	0000329	cellular_component	fungal-type vacuole membrane
o	0005515	molecular_function	protein binding
o	0005773	cellular_component	vacuole
o	0005774	cellular_component	vacuolar membrane
o	0006811	biological_process	monoatomic ion transport
o	0007035	biological_process	vacuolar acidification
o	0016020	cellular_component	membrane
o	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
o	0033176	cellular_component	proton-transporting V-type ATPase complex
o	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
o	0034220	biological_process	monoatomic ion transmembrane transport
o	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
o	0048388	biological_process	endosomal lumen acidification
o	0061795	biological_process	Golgi lumen acidification
o	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSINTSVSYS

Chain	Residue	Details
A	PRO453-SER462
D	PRO371-SER380

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: N-acetylserine => ECO:0000269\|Ref.5, ECO:0007744\|PubMed:22814378

Chain	Residue	Details
I	SER2
K	SER2
M	SER2
i	SER2
k	SER2
m	SER2

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:15665377, ECO:0007744\|PubMed:18407956

Chain	Residue	Details
D	SER4
E	SER4
F	SER4
d	SER4
e	SER4
f	SER4

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18407956, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
D	SER137
E	SER137
F	SER137
d	SER137
e	SER137
f	SER137

site_id	SWS_FT_FI4
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18407956

Chain	Residue	Details
D	SER503
e	SER504
f	SER503
f	SER504
D	SER504
E	SER503
E	SER504
F	SER503
F	SER504
d	SER503
d	SER504
e	SER503

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: Phosphoserine; by ATM or ATR => ECO:0007744\|PubMed:17330950, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
D	SER511
E	SER511
F	SER511
d	SER511
e	SER511
f	SER511

site_id	SWS_FT_FI6
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17330950, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
D	SER515
E	SER515
F	SER515
d	SER515
e	SER515
f	SER515

site_id	SWS_FT_FI7
Number of Residues	18
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744\|PubMed:22106047

Chain	Residue	Details
D	LYS14
d	LYS14
d	LYS508
e	LYS14
e	LYS508
f	LYS14
f	LYS508
D	LYS508
E	LYS14
E	LYS508
F	LYS14
F	LYS508

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
A	CYS284	covalent catalysis
A	SER359	electrostatic stabiliser
A	TRP361	electrostatic stabiliser
A	ALA362	proton shuttle (general acid/base)
A	SER584	proton shuttle (general acid/base)

site_id	MCSA2
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
B	CYS284	covalent catalysis
B	SER359	electrostatic stabiliser
B	TRP361	electrostatic stabiliser
B	ALA362	proton shuttle (general acid/base)
B	SER584	proton shuttle (general acid/base)

site_id	MCSA3
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
C	CYS284	covalent catalysis
C	SER359	electrostatic stabiliser
C	TRP361	electrostatic stabiliser
C	ALA362	proton shuttle (general acid/base)
C	SER584	proton shuttle (general acid/base)

site_id	MCSA4
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
a	CYS284	covalent catalysis
a	SER359	electrostatic stabiliser
a	TRP361	electrostatic stabiliser
a	ALA362	proton shuttle (general acid/base)
a	SER584	proton shuttle (general acid/base)

site_id	MCSA5
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
b	CYS284	covalent catalysis
b	SER359	electrostatic stabiliser
b	TRP361	electrostatic stabiliser
b	ALA362	proton shuttle (general acid/base)
b	SER584	proton shuttle (general acid/base)

site_id	MCSA6
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
c	CYS284	covalent catalysis
c	SER359	electrostatic stabiliser
c	TRP361	electrostatic stabiliser
c	ALA362	proton shuttle (general acid/base)
c	SER584	proton shuttle (general acid/base)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)