Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | binding site for residue 4ZK A 301 |
Chain | Residue |
A | TYR58 |
A | TYR187 |
A | LEU188 |
A | LEU189 |
A | GLU190 |
A | MET193 |
A | TYR217 |
A | HOH417 |
A | PRO86 |
A | LEU87 |
A | THR88 |
A | ARG93 |
A | LEU135 |
A | SER139 |
A | THR140 |
A | THR171 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue GOL A 302 |
Chain | Residue |
A | ILE89 |
A | PRO102 |
A | PRO102 |
A | LYS215 |
A | GLY216 |
A | LEU236 |
A | ASN239 |
A | HOH470 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue GOL A 303 |
Chain | Residue |
A | LYS57 |
A | TYR58 |
A | GLY59 |
A | ALA60 |
A | ASN69 |
A | ARG93 |
A | SO4309 |
A | HOH417 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue GOL A 304 |
Chain | Residue |
A | GLU10 |
A | TYR58 |
A | LEU135 |
A | THR170 |
A | THR171 |
A | HOH478 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 305 |
Chain | Residue |
A | HIS20 |
A | LYS141 |
A | ARG145 |
A | ARG160 |
A | HOH403 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 306 |
Chain | Residue |
A | LYS79 |
A | LYS113 |
A | SO4308 |
A | HOH413 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 307 |
Chain | Residue |
A | LYS148 |
A | ARG169 |
A | GLN241 |
A | HOH409 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 308 |
Chain | Residue |
A | ILE67 |
A | LYS113 |
A | LYS182 |
A | SO4306 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 309 |
Chain | Residue |
A | LYS57 |
A | SER137 |
A | GLY138 |
A | GOL303 |
A | HOH414 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 310 |
Chain | Residue |
A | ILE149 |
A | ALA150 |
A | LYS246 |
A | HOH490 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue ACT A 311 |
Chain | Residue |
A | LYS114 |
A | GLU198 |
A | MET206 |
A | HOH449 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | PRO86 | |
A | THR88 | |
A | ARG93 | |
A | SER139 | |
A | THR140 | |
A | GLU190 | |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
A | ARG61 | |
A | ARG145 | |
A | LYS237 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
A | ILE118 | |
Chain | Residue | Details |
A | SER147 | |
Chain | Residue | Details |
A | SER181 | |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |