Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| A | 0016055 | biological_process | Wnt signaling pathway |
| A | 0032212 | biological_process | positive regulation of telomere maintenance via telomerase |
| A | 0051225 | biological_process | spindle assembly |
| B | 0003950 | molecular_function | NAD+ ADP-ribosyltransferase activity |
| B | 0016055 | biological_process | Wnt signaling pathway |
| B | 0032212 | biological_process | positive regulation of telomere maintenance via telomerase |
| B | 0051225 | biological_process | spindle assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 701 |
| Chain | Residue |
| A | ALA601 |
| A | LYS602 |
| A | LYS633 |
| A | HOH809 |
| B | ASN626 |
| B | HOH878 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 702 |
| Chain | Residue |
| A | HIS614 |
| A | ARG623 |
| A | HOH869 |
| B | GLN613 |
| A | GLU576 |
| A | LYS580 |
| A | LYS592 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 703 |
| Chain | Residue |
| A | ARG538 |
| A | VAL539 |
| A | SER540 |
| A | LYS557 |
| A | HOH805 |
| A | HOH825 |
| A | HOH856 |
| A | HOH868 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 704 |
| Chain | Residue |
| A | CYS512 |
| A | HIS548 |
| B | HIS548 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 701 |
| Chain | Residue |
| A | LYS633 |
| A | ASP634 |
| A | HOH848 |
| B | GLY603 |
| B | LYS604 |
| B | TYR605 |
| B | GLU606 |
| B | HOH811 |
| B | HOH815 |
| B | HOH861 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 702 |
| Chain | Residue |
| B | LYS592 |
| B | GLN613 |
| B | HIS614 |
| B | ARG623 |
| B | HOH806 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 703 |
| Chain | Residue |
| B | ASN537 |
| B | ARG538 |
| B | VAL539 |
| B | SER540 |
| B | LYS557 |
| B | HOH802 |
| B | HOH825 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 704 |
| Chain | Residue |
| B | TYR605 |
| B | LYS609 |
| B | ASP624 |
| B | GLY625 |
| B | HOH827 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 705 |
| Chain | Residue |
| B | LYS555 |
| B | ASP556 |
| B | GLY559 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ACE C 0 and ARG C 1 |
| Chain | Residue |
| A | ASP589 |
| A | TRP591 |
| A | PHE593 |
| A | GLU598 |
| A | HOH879 |
| B | ASP634 |
| B | THR637 |
| C | GLU2 |
| C | HOH207 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide GLU C 8 and NH2 C 9 |
| Chain | Residue |
| A | TYR569 |
| A | HIS571 |
| A | LYS602 |
| A | HOH837 |
| B | GLU491 |
| B | ARG494 |
| C | ALA7 |
| C | 4XP100 |
| C | HOH204 |
| C | HOH206 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide GLU C 8 and NH2 C 9 |
| Chain | Residue |
| A | TYR569 |
| A | HIS571 |
| A | LYS602 |
| A | HOH837 |
| B | GLU491 |
| B | ARG494 |
| C | ALA7 |
| C | 4XP100 |
| C | HOH204 |
| C | HOH206 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4XP C 100 and ALA C 3 |
| Chain | Residue |
| A | ARG525 |
| A | TYR569 |
| B | GLU506 |
| B | THR507 |
| B | GLU523 |
| C | GLU2 |
| C | GLY4 |
| C | GLY6 |
| C | ALA7 |
| C | GLU8 |
| C | NH29 |
| C | HOH202 |
| C | HOH203 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 4XP C 100 and ALA C 7 |
| Chain | Residue |
| B | GLU506 |
| B | THR507 |
| B | GLU523 |
| C | ALA3 |
| C | GLY6 |
| C | GLU8 |
| C | NH29 |
| C | HOH203 |
| C | HOH209 |
| A | GLY535 |
| A | TYR569 |
| A | HIS571 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ACE D 0 and ARG D 1 |
| Chain | Residue |
| A | ASP634 |
| A | GLY635 |
| A | THR637 |
| B | ASP589 |
| B | TRP591 |
| B | PHE593 |
| B | GLU598 |
| D | GLU2 |
| D | HOH208 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide GLU D 8 and NH2 D 9 |
| Chain | Residue |
| A | ARG494 |
| B | TYR569 |
| B | HIS571 |
| B | LYS602 |
| B | HOH829 |
| D | ALA7 |
| D | 4XP100 |
| D | HOH201 |
| D | HOH210 |
| D | HOH212 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide GLU D 8 and NH2 D 9 |
| Chain | Residue |
| A | ARG494 |
| B | TYR569 |
| B | HIS571 |
| B | LYS602 |
| B | HOH829 |
| D | ALA7 |
| D | 4XP100 |
| D | HOH201 |
| D | HOH210 |
| D | HOH212 |
| site_id | AD9 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide 4XP D 100 and ALA D 7 |
| Chain | Residue |
| A | ARG494 |
| A | GLU506 |
| A | GLU523 |
| B | GLY535 |
| B | TYR569 |
| B | HIS571 |
| D | ALA3 |
| D | GLY6 |
| D | GLU8 |
| D | NH29 |
| D | HOH205 |
| D | HOH209 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 4XP D 100 and ALA D 3 |
| Chain | Residue |
| A | ARG494 |
| A | GLU506 |
| A | GLU523 |
| B | ARG525 |
| B | TYR569 |
| D | GLU2 |
| D | GLY4 |
| D | GLY6 |
| D | ALA7 |
| D | GLU8 |
| D | HOH203 |
| D | HOH205 |
| D | HOH215 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASN518 | |
| A | ASN586 | |
| B | ASN518 | |
| B | ASN586 | |
| Chain | Residue | Details |
| A | HIS553 | |
| B | HIS553 | |
