Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033192 | molecular_function | calmodulin-dependent protein phosphatase activity |
| A | 0097720 | biological_process | calcineurin-mediated signaling |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0008597 | molecular_function | calcium-dependent protein serine/threonine phosphatase regulator activity |
| C | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | ASP136 |
| A | ASN168 |
| A | HIS217 |
| A | HIS299 |
| A | FE402 |
| A | MES403 |
| A | HOH851 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue FE A 402 |
| Chain | Residue |
| A | ASP136 |
| A | ZN401 |
| A | MES403 |
| A | HOH851 |
| A | HOH852 |
| A | ASP108 |
| A | HIS110 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue MES A 403 |
| Chain | Residue |
| A | HIS110 |
| A | ASP136 |
| A | ASN168 |
| A | HIS169 |
| A | ARG272 |
| A | HIS299 |
| A | ZN401 |
| A | FE402 |
| A | HOH713 |
| A | HOH744 |
| A | HOH851 |
| A | HOH852 |
| A | HOH853 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue MES A 404 |
| Chain | Residue |
| A | ARG140 |
| A | THR179 |
| A | LEU330 |
| A | ASP331 |
| A | HOH613 |
| A | HOH739 |
| C | ARG53 |
| C | LYS54 |
| C | GLU60 |
| C | EDO202 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ASN47 |
| A | TRP51 |
| A | HOH504 |
| A | HOH516 |
| A | HOH525 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | ILE103 |
| A | THR104 |
| A | THR129 |
| A | LYS341 |
| A | HOH520 |
| A | HOH631 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | LYS341 |
| A | HOH512 |
| A | HOH514 |
| B | LEU6 |
| B | ASP21 |
| B | TRP24 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | THR44 |
| A | LEU74 |
| A | LYS187 |
| A | TYR188 |
| A | HOH867 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | LEU97 |
| A | GLU98 |
| A | TRP163 |
| A | HOH793 |
| A | HOH802 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | SER52 |
| A | ASN60 |
| A | LEU61 |
| A | ALA62 |
| A | TRP157 |
| A | HOH863 |
| A | HOH895 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 201 |
| Chain | Residue |
| B | ASP31 |
| B | ASP33 |
| B | SER35 |
| B | THR37 |
| B | GLU39 |
| B | GLU42 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 202 |
| Chain | Residue |
| B | ASP63 |
| B | ASP65 |
| B | ASP69 |
| B | GLU74 |
| B | HOH351 |
| B | HOH359 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 203 |
| Chain | Residue |
| B | ASP100 |
| B | ASP102 |
| B | ASP104 |
| B | PHE106 |
| B | GLU111 |
| B | HOH358 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 204 |
| Chain | Residue |
| B | ASP141 |
| B | ASP143 |
| B | ASP145 |
| B | ARG147 |
| B | GLU152 |
| B | HOH400 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | ASP16 |
| B | HIS17 |
| B | GLU18 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 206 |
| Chain | Residue |
| B | PHE96 |
| B | HOH409 |
| B | HOH463 |
| B | ARG93 |
| site_id | AD8 |
| Number of Residues | 22 |
| Details | binding site for residue FK5 C 201 |
| Chain | Residue |
| A | TRP370 |
| A | SER371 |
| A | PHE374 |
| A | GLU377 |
| A | HOH855 |
| B | VAL120 |
| C | TYR36 |
| C | PHE55 |
| C | ASP56 |
| C | ARG61 |
| C | PHE64 |
| C | VAL72 |
| C | VAL73 |
| C | ILE74 |
| C | TRP77 |
| C | ALA99 |
| C | TYR100 |
| C | PHE105 |
| C | PHE117 |
| C | HOH320 |
| C | HOH347 |
| C | HOH348 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 202 |
| Chain | Residue |
| A | TYR142 |
| A | MES404 |
| A | HOH732 |
| A | HOH809 |
| C | LYS54 |
| C | PHE55 |
| C | ASP56 |
| C | GLU60 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 203 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 204 |
| Chain | Residue |
| C | GLY107 |
| C | LEU108 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DRDKSGTIErdEF |
| Chain | Residue | Details |
| B | ASP31-PHE43 | |
| B | ASP63-PHE75 | |
| B | ASP100-LEU112 | |
| B | ASP141-PHE153 | |
| site_id | PS00125 |
| Number of Residues | 6 |
| Details | SER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE |
| Chain | Residue | Details |
| A | LEU165-GLU170 | |
