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5A1U

The structure of the COPI coat triad

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006886biological_processintracellular protein transport
A0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
A0006893biological_processGolgi to plasma membrane transport
A0010636biological_processpositive regulation of mitochondrial fusion
A0015031biological_processprotein transport
A0016192biological_processvesicle-mediated transport
A0016236biological_processmacroautophagy
A0016787molecular_functionhydrolase activity
A0019217biological_processregulation of fatty acid metabolic process
A0044232cellular_componentorganelle membrane contact site
A0048193biological_processGolgi vesicle transport
A0090141biological_processpositive regulation of mitochondrial fission
A1903292biological_processprotein localization to Golgi membrane
A1903358biological_processregulation of Golgi organization
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006886biological_processintracellular protein transport
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0006893biological_processGolgi to plasma membrane transport
B0010636biological_processpositive regulation of mitochondrial fusion
B0015031biological_processprotein transport
B0016192biological_processvesicle-mediated transport
B0016236biological_processmacroautophagy
B0016787molecular_functionhydrolase activity
B0019217biological_processregulation of fatty acid metabolic process
B0044232cellular_componentorganelle membrane contact site
B0048193biological_processGolgi vesicle transport
B0090141biological_processpositive regulation of mitochondrial fission
B1903292biological_processprotein localization to Golgi membrane
B1903358biological_processregulation of Golgi organization
C0000139cellular_componentGolgi membrane
C0003729molecular_functionmRNA binding
C0005179molecular_functionhormone activity
C0005198molecular_functionstructural molecule activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005737cellular_componentcytoplasm
C0005794cellular_componentGolgi apparatus
C0006886biological_processintracellular protein transport
C0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
C0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C0006891biological_processintra-Golgi vesicle-mediated transport
C0007165biological_processsignal transduction
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0030117cellular_componentmembrane coat
C0030126cellular_componentCOPI vesicle coat
C0030137cellular_componentCOPI-coated vesicle
C0030157biological_processpancreatic juice secretion
C0030424cellular_componentaxon
C0030426cellular_componentgrowth cone
C0030663cellular_componentCOPI-coated vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
C0043025cellular_componentneuronal cell body
C0099612biological_processprotein localization to axon
C1902463biological_processprotein localization to cell leading edge
D0000139cellular_componentGolgi membrane
D0005080molecular_functionprotein kinase C binding
D0005198molecular_functionstructural molecule activity
D0005737cellular_componentcytoplasm
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0006886biological_processintracellular protein transport
D0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
D0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
D0006891biological_processintra-Golgi vesicle-mediated transport
D0015031biological_processprotein transport
D0016020cellular_componentmembrane
D0016192biological_processvesicle-mediated transport
D0030117cellular_componentmembrane coat
D0030126cellular_componentCOPI vesicle coat
D0030663cellular_componentCOPI-coated vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
E0000139cellular_componentGolgi membrane
E0005198molecular_functionstructural molecule activity
E0005737cellular_componentcytoplasm
E0005783cellular_componentendoplasmic reticulum
E0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
E0005794cellular_componentGolgi apparatus
E0005829cellular_componentcytosol
E0006886biological_processintracellular protein transport
E0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
E0006891biological_processintra-Golgi vesicle-mediated transport
E0009306biological_processprotein secretion
E0015031biological_processprotein transport
E0016020cellular_componentmembrane
E0016192biological_processvesicle-mediated transport
E0030117cellular_componentmembrane coat
E0030126cellular_componentCOPI vesicle coat
E0030663cellular_componentCOPI-coated vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0051683biological_processestablishment of Golgi localization
E0072384biological_processorganelle transport along microtubule
F0000139cellular_componentGolgi membrane
F0003674molecular_functionmolecular_function
F0005737cellular_componentcytoplasm
F0005794cellular_componentGolgi apparatus
F0006886biological_processintracellular protein transport
F0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
F0006891biological_processintra-Golgi vesicle-mediated transport
F0015031biological_processprotein transport
F0016020cellular_componentmembrane
F0016192biological_processvesicle-mediated transport
F0030117cellular_componentmembrane coat
F0030126cellular_componentCOPI vesicle coat
F0030663cellular_componentCOPI-coated vesicle membrane
F0031410cellular_componentcytoplasmic vesicle
G0000139cellular_componentGolgi membrane
G0005198molecular_functionstructural molecule activity
G0005737cellular_componentcytoplasm
G0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
G0005794cellular_componentGolgi apparatus
G0005798cellular_componentGolgi-associated vesicle
G0005829cellular_componentcytosol
G0005886cellular_componentplasma membrane
G0006886biological_processintracellular protein transport
G0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
G0006891biological_processintra-Golgi vesicle-mediated transport
G0015031biological_processprotein transport
G0016192biological_processvesicle-mediated transport
G0030117cellular_componentmembrane coat
G0030126cellular_componentCOPI vesicle coat
G0030137cellular_componentCOPI-coated vesicle
G0030663cellular_componentCOPI-coated vesicle membrane
G0031410cellular_componentcytoplasmic vesicle
G0043231cellular_componentintracellular membrane-bounded organelle
H0000139cellular_componentGolgi membrane
H0005737cellular_componentcytoplasm
H0005783cellular_componentendoplasmic reticulum
H0005794cellular_componentGolgi apparatus
H0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
H0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
H0008344biological_processadult locomotory behavior
H0015031biological_processprotein transport
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0021691biological_processcerebellar Purkinje cell layer maturation
H0030126cellular_componentCOPI vesicle coat
H0030137cellular_componentCOPI-coated vesicle
H0030663cellular_componentCOPI-coated vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
H0043473biological_processpigmentation
H0048193biological_processGolgi vesicle transport
H0051645biological_processGolgi localization
H0051649biological_processestablishment of localization in cell
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. VVSAslDqTVRVWDI
ChainResidueDetails
CVAL150-ILE164

site_idPS00989
Number of Residues11
DetailsCLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. VVYKssidLYF
ChainResidueDetails
FVAL67-PHE77

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P48444
ChainResidueDetails
HSER223
BALA160
HSER244
HSER493
AASN126
AALA160
BLEU25
BTHR48
BGLY70
BASN126

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P48444
ChainResidueDetails
HLYS233
HLYS309

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337
ChainResidueDetails
HLYS241
HLYS351
BLYS127

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P53621
ChainResidueDetails
CSER1193

222624

PDB entries from 2024-07-17

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