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4ZK0

Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure

Functional Information from GO Data
ChainGOidnamespacecontents
A0002020molecular_functionprotease binding
A0004866molecular_functionendopeptidase inhibitor activity
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0030414molecular_functionpeptidase inhibitor activity
A0031410cellular_componentcytoplasmic vesicle
A0031982cellular_componentvesicle
A0035578cellular_componentazurophil granule lumen
A0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 401
ChainResidue
AGLU64
AASP281
AHIS283
AHOH580

site_idAC2
Number of Residues3
Detailsbinding site for residue ZN A 402
ChainResidue
AGLU165
AHIS220
AGLU277

Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. FHCNHPFLFfI
ChainResidueDetails
APHE363-ILE373

244349

PDB entries from 2025-11-05

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