4ZFI
Structure of Mdm2 with low molecular weight inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
| D | 0005634 | cellular_component | nucleus |
| D | 0043066 | biological_process | negative regulation of apoptotic process |
| D | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 4NJ A 201 |
| Chain | Residue |
| A | LEU54 |
| A | HOH309 |
| A | HOH322 |
| A | HOH329 |
| A | HOH331 |
| D | LYS51 |
| A | PHE55 |
| A | GLY58 |
| A | ILE61 |
| A | TYR67 |
| A | VAL93 |
| A | HIS96 |
| A | ILE99 |
| A | TYR100 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue 4NJ B 201 |
| Chain | Residue |
| B | LEU54 |
| B | PHE55 |
| B | GLY58 |
| B | ILE61 |
| B | TYR67 |
| B | HIS96 |
| B | ILE99 |
| B | HOH310 |
| B | HOH312 |
| B | HOH327 |
| B | HOH334 |
| C | LYS51 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 4NJ C 201 |
| Chain | Residue |
| B | LYS51 |
| C | LEU54 |
| C | PHE55 |
| C | GLY58 |
| C | TYR67 |
| C | HIS96 |
| C | ILE99 |
| C | TYR100 |
| C | HOH305 |
| C | HOH311 |
| C | HOH326 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue 4NJ D 201 |
| Chain | Residue |
| A | LYS51 |
| D | LEU54 |
| D | PHE55 |
| D | GLY58 |
| D | TYR67 |
| D | VAL93 |
| D | HIS96 |
| D | ILE99 |
| D | HOH306 |
| D | HOH314 |
| D | HOH321 |
| D | HOH343 |
