4ZCF

Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0008168	molecular_function	methyltransferase activity
A	0008170	molecular_function	N-methyltransferase activity
A	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
A	0009307	biological_process	DNA restriction-modification system
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0008168	molecular_function	methyltransferase activity
B	0008170	molecular_function	N-methyltransferase activity
B	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
B	0009307	biological_process	DNA restriction-modification system
B	0016740	molecular_function	transferase activity
B	0032259	biological_process	methylation
C	0000166	molecular_function	nucleotide binding
C	0003677	molecular_function	DNA binding
C	0004386	molecular_function	helicase activity
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0005524	molecular_function	ATP binding
C	0009307	biological_process	DNA restriction-modification system
C	0015668	molecular_function	type III site-specific deoxyribonuclease activity
C	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue MN A 701

Chain	Residue
A	HIS201

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MN A 702

Chain	Residue
A	GLU213
C	HIS168

---

site_id	AC3
Number of Residues	13
Details	binding site for residue AMP C 1001

Chain	Residue
C	GLY122
C	THR123
C	PHE126
C	ASP226
C	GLU227
C	ASP509
C	ARG537
C	GLN14
C	GLY89
C	LYS90
C	THR91
C	TYR92
C	ILE119

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CA D 101

Chain	Residue
B	HOH717
B	HOH723
D	DA8
D	HOH202

---

Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. IYIDPPY

Chain	Residue	Details
A	ILE120-TYR126

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:26067164, ECO:0007744|PDB:4ZCF

Chain	Residue	Details
C	THR91
C	GLY122
C	PHE126
C	ASP226

---