4YZN

Humanized Roco4 bound to Compound 19

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004713	molecular_function	protein tyrosine kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue 4K5 A 1301

Chain	Residue
A	ILE1032
A	ASP1177
A	HOH1405
A	HOH1444
A	VAL1040
A	ALA1053
A	MET1105
A	GLU1106
A	VAL1108
A	PRO1109
A	GLY1111
A	LEU1161

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Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGGFGLVHkGrlvkdksv..........VAIK

Chain	Residue	Details
A	ILE1032-LYS1055

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ASP1154

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ILE1032
A	LYS1055

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