Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4YHH

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline

Functional Information from GO Data
ChainGOidnamespacecontents
B0003735molecular_functionstructural constituent of ribosome
B0005840cellular_componentribosome
B0006412biological_processtranslation
B0015935cellular_componentsmall ribosomal subunit
C0003676molecular_functionnucleic acid binding
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0006412biological_processtranslation
D0003723molecular_functionRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005840cellular_componentribosome
D0006412biological_processtranslation
D0015935cellular_componentsmall ribosomal subunit
D0019843molecular_functionrRNA binding
D0042274biological_processribosomal small subunit biogenesis
D0046872molecular_functionmetal ion binding
D1990904cellular_componentribonucleoprotein complex
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0005737cellular_componentcytoplasm
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0015935cellular_componentsmall ribosomal subunit
E0019843molecular_functionrRNA binding
E1990904cellular_componentribonucleoprotein complex
F0003735molecular_functionstructural constituent of ribosome
F0005737cellular_componentcytoplasm
F0005840cellular_componentribosome
F0006412biological_processtranslation
F0019843molecular_functionrRNA binding
F0070181molecular_functionsmall ribosomal subunit rRNA binding
F1990904cellular_componentribonucleoprotein complex
G0000028biological_processribosomal small subunit assembly
G0000049molecular_functiontRNA binding
G0003723molecular_functionRNA binding
G0003729molecular_functionmRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0005840cellular_componentribosome
G0006412biological_processtranslation
G0015935cellular_componentsmall ribosomal subunit
G0019843molecular_functionrRNA binding
G0022627cellular_componentcytosolic small ribosomal subunit
G1990904cellular_componentribonucleoprotein complex
H0003735molecular_functionstructural constituent of ribosome
H0005737cellular_componentcytoplasm
H0005840cellular_componentribosome
H0006412biological_processtranslation
H0019843molecular_functionrRNA binding
H0022627cellular_componentcytosolic small ribosomal subunit
H1990904cellular_componentribonucleoprotein complex
I0000049molecular_functiontRNA binding
I0003723molecular_functionRNA binding
I0003735molecular_functionstructural constituent of ribosome
I0005840cellular_componentribosome
I0006412biological_processtranslation
I0015935cellular_componentsmall ribosomal subunit
I0019843molecular_functionrRNA binding
I1990904cellular_componentribonucleoprotein complex
J0000049molecular_functiontRNA binding
J0003723molecular_functionRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0005840cellular_componentribosome
J0006412biological_processtranslation
J0015935cellular_componentsmall ribosomal subunit
J0019843molecular_functionrRNA binding
J1990904cellular_componentribonucleoprotein complex
K0003735molecular_functionstructural constituent of ribosome
K0005840cellular_componentribosome
K0006412biological_processtranslation
L0000049molecular_functiontRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005840cellular_componentribosome
L0006412biological_processtranslation
L0015935cellular_componentsmall ribosomal subunit
L0019843molecular_functionrRNA binding
L1990904cellular_componentribonucleoprotein complex
M0000049molecular_functiontRNA binding
M0003676molecular_functionnucleic acid binding
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
M0006412biological_processtranslation
M0015935cellular_componentsmall ribosomal subunit
M0019843molecular_functionrRNA binding
M1990904cellular_componentribonucleoprotein complex
N0003735molecular_functionstructural constituent of ribosome
N0005737cellular_componentcytoplasm
N0005840cellular_componentribosome
N0006412biological_processtranslation
N0008270molecular_functionzinc ion binding
N0015935cellular_componentsmall ribosomal subunit
N0019843molecular_functionrRNA binding
N0046872molecular_functionmetal ion binding
N1990904cellular_componentribonucleoprotein complex
O0003735molecular_functionstructural constituent of ribosome
O0005737cellular_componentcytoplasm
O0005840cellular_componentribosome
O0006412biological_processtranslation
O0019843molecular_functionrRNA binding
O0022627cellular_componentcytosolic small ribosomal subunit
O1990904cellular_componentribonucleoprotein complex
P0003735molecular_functionstructural constituent of ribosome
P0005737cellular_componentcytoplasm
P0005840cellular_componentribosome
P0006412biological_processtranslation
P0015935cellular_componentsmall ribosomal subunit
P1990904cellular_componentribonucleoprotein complex
Q0003735molecular_functionstructural constituent of ribosome
Q0005840cellular_componentribosome
Q0006412biological_processtranslation
Q0019843molecular_functionrRNA binding
Q0022627cellular_componentcytosolic small ribosomal subunit
Q1990904cellular_componentribonucleoprotein complex
R0003735molecular_functionstructural constituent of ribosome
R0005840cellular_componentribosome
R0006412biological_processtranslation
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005840cellular_componentribosome
S0006412biological_processtranslation
S0015935cellular_componentsmall ribosomal subunit
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005829cellular_componentcytosol
T0005840cellular_componentribosome
T0006412biological_processtranslation
T0015935cellular_componentsmall ribosomal subunit
T0019843molecular_functionrRNA binding
T0070181molecular_functionsmall ribosomal subunit rRNA binding
T1990904cellular_componentribonucleoprotein complex
V0005840cellular_componentribosome
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue T1C A 1601
ChainResidue
AU531
AMG1702
AA965
AG966
AG1053
AC1054
AC1195
AG1197
AG1198
AMG1688

site_idAC2
Number of Residues3
Detailsbinding site for residue MG A 1602
ChainResidue
AU13
AU14
AA16

site_idAC3
Number of Residues2
Detailsbinding site for residue MG A 1603
ChainResidue
AG21
AG567

site_idAC4
Number of Residues2
Detailsbinding site for residue MG A 1605
ChainResidue
AU37
AG38

site_idAC5
Number of Residues1
Detailsbinding site for residue MG A 1606
ChainResidue
AG41

site_idAC6
Number of Residues2
Detailsbinding site for residue MG A 1608
ChainResidue
AA53
AA353

site_idAC7
Number of Residues2
Detailsbinding site for residue MG A 1609
ChainResidue
AU95
AG96

site_idAC8
Number of Residues2
Detailsbinding site for residue MG A 1610
ChainResidue
AG111
AG112

site_idAC9
Number of Residues4
Detailsbinding site for residue MG A 1611
ChainResidue
AC47
AC48
AA51
AG115

site_idAD1
Number of Residues1
Detailsbinding site for residue MG A 1613
ChainResidue
AU173

site_idAD2
Number of Residues1
Detailsbinding site for residue MG A 1614
ChainResidue
AA151

site_idAD3
Number of Residues2
Detailsbinding site for residue MG A 1615
ChainResidue
AC174
AC175

site_idAD4
Number of Residues3
Detailsbinding site for residue MG A 1616
ChainResidue
AA179
AG181
AA195

site_idAD5
Number of Residues2
Detailsbinding site for residue MG A 1617
ChainResidue
AG285
AG286

site_idAD6
Number of Residues4
Detailsbinding site for residue MG A 1618
ChainResidue
AA116
AG117
AA288
AG289

site_idAD7
Number of Residues3
Detailsbinding site for residue MG A 1619
ChainResidue
AC290
AC291
AG305

site_idAD8
Number of Residues2
Detailsbinding site for residue MG A 1620
ChainResidue
AG297
AA298

site_idAD9
Number of Residues2
Detailsbinding site for residue MG A 1621
ChainResidue
AC307
AC308

site_idAE1
Number of Residues1
Detailsbinding site for residue MG A 1622
ChainResidue
AA315

site_idAE2
Number of Residues2
Detailsbinding site for residue MG A 1623
ChainResidue
AU323
AG324

site_idAE3
Number of Residues2
Detailsbinding site for residue MG A 1624
ChainResidue
AC330
AC352

site_idAE4
Number of Residues1
Detailsbinding site for residue MG A 1625
ChainResidue
AG376

site_idAE5
Number of Residues2
Detailsbinding site for residue MG A 1626
ChainResidue
AG35
AC398

site_idAE6
Number of Residues3
Detailsbinding site for residue MG A 1627
ChainResidue
AG409
AG410
AA431

site_idAE7
Number of Residues2
Detailsbinding site for residue MG A 1628
ChainResidue
AG450
AA452

site_idAE8
Number of Residues1
Detailsbinding site for residue MG A 1629
ChainResidue
AG492

site_idAE9
Number of Residues3
Detailsbinding site for residue MG A 1630
ChainResidue
AG506
AA509
AA510

site_idAF1
Number of Residues4
Detailsbinding site for residue MG A 1631
ChainResidue
AC514
AG515
AU516
AA533

site_idAF2
Number of Residues1
Detailsbinding site for residue MG A 1632
ChainResidue
AC536

site_idAF3
Number of Residues1
Detailsbinding site for residue MG A 1633
ChainResidue
AC536

site_idAF4
Number of Residues3
Detailsbinding site for residue MG A 1634
ChainResidue
AG402
AA547
AG548

site_idAF5
Number of Residues3
Detailsbinding site for residue MG A 1635
ChainResidue
AA298
AG299
AG558

site_idAF6
Number of Residues2
Detailsbinding site for residue MG A 1636
ChainResidue
AU560
AC562

site_idAF7
Number of Residues1
Detailsbinding site for residue MG A 1637
ChainResidue
AA572

site_idAF8
Number of Residues4
Detailsbinding site for residue MG A 1638
ChainResidue
AU571
AA572
AA573
AA574

site_idAF9
Number of Residues2
Detailsbinding site for residue MG A 1639
ChainResidue
AG576
AG577

site_idAG1
Number of Residues2
Detailsbinding site for residue MG A 1640
ChainResidue
AG581
AG758

site_idAG2
Number of Residues2
Detailsbinding site for residue MG A 1641
ChainResidue
AG588
AC645

site_idAG3
Number of Residues4
Detailsbinding site for residue MG A 1643
ChainResidue
AG595
AC596
AG597
AU598

site_idAG4
Number of Residues2
Detailsbinding site for residue MG A 1644
ChainResidue
AA608
AG610

site_idAG5
Number of Residues3
Detailsbinding site for residue MG A 1645
ChainResidue
AG610
AC624
AG625

site_idAG6
Number of Residues1
Detailsbinding site for residue MG A 1646
ChainResidue
AC620

site_idAG7
Number of Residues1
Detailsbinding site for residue MG A 1647
ChainResidue
AC612

site_idAG8
Number of Residues2
Detailsbinding site for residue MG A 1648
ChainResidue
AU636
AMG1649

site_idAG9
Number of Residues3
Detailsbinding site for residue MG A 1649
ChainResidue
AG637
AG638
AMG1648

site_idAH1
Number of Residues1
Detailsbinding site for residue MG A 1650
ChainResidue
AG595

site_idAH2
Number of Residues2
Detailsbinding site for residue MG A 1651
ChainResidue
AG649
AG650

site_idAH3
Number of Residues1
Detailsbinding site for residue MG A 1652
ChainResidue
AG683

site_idAH4
Number of Residues1
Detailsbinding site for residue MG A 1655
ChainResidue
AG730

site_idAH5
Number of Residues3
Detailsbinding site for residue MG A 1656
ChainResidue
AC748
AC749
AG750

site_idAH6
Number of Residues3
Detailsbinding site for residue MG A 1658
ChainResidue
AA766
AC811
AC812

site_idAH7
Number of Residues2
Detailsbinding site for residue MG A 1659
ChainResidue
AA767
AA768

site_idAH8
Number of Residues2
Detailsbinding site for residue MG A 1660
ChainResidue
AG773
AG774

site_idAH9
Number of Residues3
Detailsbinding site for residue MG A 1661
ChainResidue
AC797
AG798
AG799

site_idAI1
Number of Residues5
Detailsbinding site for residue MG A 1662
ChainResidue
AA782
AC783
AU793
AA794
AC1515

site_idAI2
Number of Residues2
Detailsbinding site for residue MG A 1663
ChainResidue
AG771
AU804

site_idAI3
Number of Residues2
Detailsbinding site for residue MG A 1665
ChainResidue
AG576
AC578

site_idAI4
Number of Residues3
Detailsbinding site for residue MG A 1667
ChainResidue
AC857
AG858
AG869

site_idAI5
Number of Residues2
Detailsbinding site for residue MG A 1668
ChainResidue
AA860
AG861

site_idAI6
Number of Residues2
Detailsbinding site for residue MG A 1669
ChainResidue
AA864
EGLU83

site_idAI7
Number of Residues3
Detailsbinding site for residue MG A 1671
ChainResidue
AU813
AA814
AC904

site_idAI8
Number of Residues2
Detailsbinding site for residue MG A 1672
ChainResidue
AC934
AU1345

site_idAI9
Number of Residues2
Detailsbinding site for residue MG A 1673
ChainResidue
AA937
AG939

site_idAJ1
Number of Residues2
Detailsbinding site for residue MG A 1674
ChainResidue
AG963
AC1200

site_idAJ2
Number of Residues2
Detailsbinding site for residue MG A 1675
ChainResidue
AA964
AU1199

site_idAJ3
Number of Residues2
Detailsbinding site for residue MG A 1676
ChainResidue
AC972
JASP58

site_idAJ4
Number of Residues4
Detailsbinding site for residue MG A 1677
ChainResidue
AG1053
AC1054
AG1197
AG1198

site_idAJ5
Number of Residues2
Detailsbinding site for residue MG A 1678
ChainResidue
AC1066
AA1067

site_idAJ6
Number of Residues2
Detailsbinding site for residue MG A 1679
ChainResidue
AC1069
AU1085

site_idAJ7
Number of Residues2
Detailsbinding site for residue MG A 1680
ChainResidue
AG1077
AG1079

site_idAJ8
Number of Residues1
Detailsbinding site for residue MG A 1681
ChainResidue
AU1086

site_idAJ9
Number of Residues3
Detailsbinding site for residue MG A 1682
ChainResidue
AG1068
AG1094
AG1387

site_idAK1
Number of Residues2
Detailsbinding site for residue MG A 1683
ChainResidue
AU1095
AG1108

site_idAK2
Number of Residues2
Detailsbinding site for residue MG A 1684
ChainResidue
AU1085
AC1103

site_idAK3
Number of Residues2
Detailsbinding site for residue MG A 1685
ChainResidue
AA1110
AC1189

site_idAK4
Number of Residues4
Detailsbinding site for residue MG A 1688
ChainResidue
AC1054
AG1197
AG1198
AT1C1601

site_idAK5
Number of Residues1
Detailsbinding site for residue MG A 1689
ChainResidue
AA1204

site_idAK6
Number of Residues5
Detailsbinding site for residue MG A 1690
ChainResidue
AC979
AC980
AU981
AG1221
AG1222

site_idAK7
Number of Residues2
Detailsbinding site for residue MG A 1691
ChainResidue
AG951
AG1224

site_idAK8
Number of Residues2
Detailsbinding site for residue MG A 1692
ChainResidue
AG1265
AG1266

site_idAK9
Number of Residues1
Detailsbinding site for residue MG A 1693
ChainResidue
AG1271

site_idAL1
Number of Residues2
Detailsbinding site for residue MG A 1694
ChainResidue
AA1238
AC1335

site_idAL2
Number of Residues1
Detailsbinding site for residue MG A 1695
ChainResidue
AG1355

site_idAL3
Number of Residues2
Detailsbinding site for residue MG A 1696
ChainResidue
AC980
AA1360

site_idAL4
Number of Residues1
Detailsbinding site for residue MG A 1697
ChainResidue
AG1370

site_idAL5
Number of Residues5
Detailsbinding site for residue MG A 1699
ChainResidue
AU1498
AA1499
AA1500
AG1504
AG1505

site_idAL6
Number of Residues5
Detailsbinding site for residue MG A 1700
ChainResidue
AA1500
AG1504
AG1505
AA1507
AG1508

site_idAL7
Number of Residues1
Detailsbinding site for residue MG A 1701
ChainResidue
AG1526

site_idAL8
Number of Residues2
Detailsbinding site for residue MG A 1702
ChainResidue
AG966
AT1C1601

site_idAL9
Number of Residues3
Detailsbinding site for residue MG A 1703
ChainResidue
AC1303
AG1304
VASP5

site_idAM1
Number of Residues6
Detailsbinding site for residue ZN D 301
ChainResidue
DCYS9
DCYS12
DLEU19
DLYS22
DCYS26
DCYS31

site_idAM2
Number of Residues2
Detailsbinding site for residue MG E 201
ChainResidue
AG21
EGLY124

site_idAM3
Number of Residues4
Detailsbinding site for residue ZN N 101
ChainResidue
NCYS24
NCYS27
NCYS40
NCYS43

Functional Information from PROSITE/UniProt
site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. DvLvtaFInkimrdGKKnlaarIFydA
ChainResidueDetails
GASP20-ALA46

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GiaILSTSkGVLtdreAR
ChainResidueDetails
HGLY108-ARG125

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaS.GLqVksivDdTPvPHN
ChainResidueDetails
KILE95-ASN117

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR
ChainResidueDetails
LLYS46-ARG53

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIiEsRPIS
ChainResidueDetails
QGLY54-SER66

site_idPS00057
Number of Residues24
DetailsRIBOSOMAL_S18 Ribosomal protein S18 signature. RDYrn.VevLkrFLSEt.GKIlprRR
ChainResidueDetails
RARG32-ARG55

site_idPS00063
Number of Residues16
DetailsALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LAKTIKraRIlGLlPF
ChainResidueDetails
RLEU66-PHE81

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKqhvpvyItenmVGhkLGEFapT
ChainResidueDetails
SASN53-THR77

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGksGQidAiklGiARAL
ChainResidueDetails
IGLY67-LEU85

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. ArrsGAqvsGPIpLPT
ChainResidueDetails
JALA27-THR42

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. LseHLkvhKkDhhShrgLlmMvgqrrrLlrY
ChainResidueDetails
OLEU39-TYR69

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. R.CvrcgrarsvyrfFGLCRiCLR
ChainResidueDetails
NARG23-ARG45

site_idPS00548
Number of Residues35
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewaaqGrVplHt..LranIDygfalarTtyGvlG
ChainResidueDetails
CALA163-GLY197

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFgAlvVVGDrq.GrVGlGfgkap.EVpl.AV
ChainResidueDetails
EGLY23-VAL55

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRlgfAvSrrqARqLV
ChainResidueDetails
DLEU97-VAL121

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ
ChainResidueDetails
MARG88-GLN101

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VkELLEAGVHFG
ChainResidueDetails
BVAL7-GLY18

site_idPS01048
Number of Residues10
DetailsRIBOSOMAL_S6 Ribosomal protein S6 signature. GlRRLAYpIA
ChainResidueDetails
FGLY44-ALA53

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: 3-methylthioaspartic acid => ECO:0000269|PubMed:16287167, ECO:0000269|PubMed:25775268
ChainResidueDetails
LASP92
DCYS12
DCYS26
DCYS31

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon