Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 49W A 400 |
| Chain | Residue |
| A | ILE32 |
| A | ASP214 |
| A | GLY216 |
| A | THR217 |
| A | SER218 |
| A | ILE290 |
| A | LEU292 |
| A | ILE300 |
| A | ASP34 |
| A | GLY36 |
| A | TYR77 |
| A | VAL78 |
| A | SER79 |
| A | PHE111 |
| A | THR114 |
| A | ILE123 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 49W B 401 |
| Chain | Residue |
| B | MET15 |
| B | ILE32 |
| B | ASP34 |
| B | VAL78 |
| B | SER79 |
| B | PHE111 |
| B | ILE123 |
| B | TYR192 |
| B | ASP214 |
| B | GLY216 |
| B | THR217 |
| B | SER218 |
| B | LEU292 |
| B | ILE300 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue 49W C 401 |
| Chain | Residue |
| C | ILE32 |
| C | ASP34 |
| C | GLY36 |
| C | VAL78 |
| C | SER79 |
| C | PHE111 |
| C | THR114 |
| C | ILE123 |
| C | TYR192 |
| C | ASP214 |
| C | GLY216 |
| C | THR217 |
| C | SER218 |
| C | LEU292 |
| C | ILE300 |
| C | GOL403 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | ASP279 |
| D | THR48 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | MET75 |
| C | ASN76 |
| C | ILE133 |
| C | 49W401 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue 49W D 400 |
| Chain | Residue |
| D | MET15 |
| D | ILE32 |
| D | ASP34 |
| D | GLY36 |
| D | VAL78 |
| D | SER79 |
| D | PHE111 |
| D | THR114 |
| D | SER118 |
| D | ILE123 |
| D | TYR192 |
| D | ASP214 |
| D | GLY216 |
| D | THR217 |
| D | SER218 |
| D | ILE300 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1228 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
