4XW2
Structural basis for simvastatin competitive antagonism of complement receptor 3
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | SER142 |
| A | SER144 |
| A | THR209 |
| A | SIM402 |
| A | HOH563 |
| A | HOH564 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue SIM A 402 |
| Chain | Residue |
| A | ARG151 |
| A | LYS154 |
| A | SER158 |
| A | ARG196 |
| A | LYS200 |
| A | GLY207 |
| A | ARG208 |
| A | THR209 |
| A | PHE246 |
| A | MG401 |
| A | HOH502 |
| A | HOH564 |
| A | SER142 |
| A | GLY143 |
| A | SER144 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 178 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
