4XJ4

Crystal structure of Vibrio cholerae DncV 3'-deoxy ATP bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0140701	molecular_function	3',3'-cyclic GMP-AMP synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 1001

Chain	Residue
A	LYS29
A	PHE115
A	ASP118
A	LEU120
A	ARG284
A	HOH1199

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 1002

Chain	Residue
A	GLY398
A	HOH1230
A	HOH1370
A	ALA292
A	ASN394
A	MET395

---

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 1003

Chain	Residue
A	PHE7
A	TYR11
A	GLY323
A	LEU377
A	GLU381
A	ILE393

---

site_id	AC4
Number of Residues	4
Details	binding site for residue EDO A 1004

Chain	Residue
A	TRP5
A	GLU381
A	SER382
A	ALA383

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 1005

Chain	Residue
A	PRO334
A	SER335
A	ALA338
A	GLU371
A	HOH1246
A	HOH1308

---

site_id	AC6
Number of Residues	21
Details	binding site for residue 3AT A 1006

Chain	Residue
A	GLN112
A	GLY113
A	SER114
A	TYR117
A	ASP131
A	ASP133
A	LYS287
A	SER301
A	LEU352
A	3AT1007
A	MG1008
A	HOH1187
A	HOH1188
A	HOH1198
A	HOH1201
A	HOH1203
A	HOH1256
A	HOH1260
A	HOH1270
A	HOH1291
A	HOH1379

---

site_id	AC7
Number of Residues	9
Details	binding site for residue 3AT A 1007

Chain	Residue
A	GLN112
A	ASP133
A	LYS177
A	THR179
A	ARG182
A	SER259
A	3AT1006
A	HOH1225
A	HOH1380

---

site_id	AC8
Number of Residues	4
Details	binding site for residue MG A 1008

Chain	Residue
A	ASP131
A	ASP133
A	3AT1006
A	HOH1187

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TXY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TXZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TY0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25131990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25201413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25865248","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XJ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---